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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Management and survival of patients admitted with an exacerbation of COPD: comparison of two Danish patient cohorts

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  1. Gene-environment interaction in atopic diseases: a population-based twin study of early life exposures

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  2. Trefoil factor peptides in serum and sputum from subjects with asthma and COPD

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  3. The effect of rehabilitation on health-care utilisation in COPD patients in Copenhagen

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  4. Improving Quality of Care among COPD outpatients in Denmark 2008-2011

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  5. Impact of diagnostic criteria on the prevalence of COPD

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  1. ERS and tobacco harm reduction

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  2. β2-Adrenergic genotypes and risk of severe exacerbations in COPD: a prospective cohort study

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  3. Prognostic significance of chronic respiratory symptoms in individuals with normal spirometry

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  4. Prognosis of COPD depends on severity of exacerbation history: A population-based analysis

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INTRODUCTION:  The aim of this study was to describe the management and prognosis related to a hospital admission for acute exacerbation of chronic obstructive pulmonary disease and to compare results to an earlier study. OBJECTIVES AND METHODS:  This is a retrospective study of 300 consecutively discharged patients admitted in 2006-2007 with an exacerbation of chronic obstructive pulmonary disease from three respiratory departments. Data were collected from patient charts and compared with a replicate study done in 2001. RESULTS:  The mean age was 72.1years; 61.7% were women. Mean forced expiratory volume in 1s was 37.6% of predicted. On admission, 11.3% were treated with non-invasive ventilation, and 84.3% were given systemic corticosteroids. In-hospital mortality was 4.7%. At discharge, treatment with inhaled corticosteroids or at least one long-acting bronchodilator was given to 86.7% and 89% of patients, respectively, which was significantly higher than for similarly sampled patients in 2001. Mortality in 30days and 1year after discharge was 4.5% and 25.5%, respectively, compared with 5.5% and 30.3% in 2001, the 12-month mortality being significantly lower (P=0.03). Readmission rate in the 12months following discharge was 42.3%. Long-term oxygen treatment, treatment with anti-dysrhythmic drugs and lack of outpatient follow-up were independent predictors of 1-year mortality. Risk of readmission was increased with dependence in self-care activities, previous admissions and treatment with strong analgesics. CONCLUSIONS:  Over a period of 6years, a significantly higher number of patients are being treated according to guidelines. Survival following discharge increased over the same period.
Original languageEnglish
JournalThe clinical respiratory journal
Volume4
Issue number4
Pages (from-to)208-14
Number of pages6
DOIs
Publication statusPublished - 2010

ID: 32568694