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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Relation of Serum Adiponectin Levels to Number of Traditional Atherosclerotic Risk Factors and All-Cause Mortality and Major Adverse Cardiovascular Events (from the Copenhagen City Heart Study)

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  1. Causes of Mortality in the Marfan Syndrome(from a Nationwide Register Study)

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  2. Usefulness of Transcatheter Aortic Valve Implantation for Treatment of Pure Native Aortic Valve Regurgitation

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  1. Prognostic value of ratio of transmitral early filling velocity to early diastolic strain rate in patients with Type 2 diabetes

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  2. Low serum adiponectin is associated with the metabolic syndrome and adds to cardiovascular risk in individuals with type 1 diabetes without nephropathy

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  3. The effect of liraglutide on natriuretic peptides and copeptin in heart failure patients

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  4. An echocardiographic substrate for dyspnea identifies high risk patients with type 2 diabetes

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Adiponectin exerts anti-inflammatory and antiatherogenic effects and appears to protect against arteriosclerosis. Accordingly, an association between low concentrations of plasma adiponectin and cardiovascular (CV) disease has been demonstrated in several studies. In contrast, elevated plasma adiponectin has been associated with increased mortality and an increasing number of major adverse CV events (MACE). Because of these conflicting results, the true role of adiponectin remains to be elucidated. In the Copenhagen City Heart Study, we prospectively followed up 5,624 randomly selected men and women from the community without CV disease. Plasma adiponectin was measured at the beginning of the study. The median follow-up time was 7.8 years (interquartile range 7.3 to 8.3). The end point was all-cause mortality (n = 801), and the combined end point was MACE, consisting of CV mortality or nonfatal myocardial infarction or ischemic stroke (n = 502). High adiponectin was inversely associated with an increasing number of traditional CV risk factors (p
Original languageEnglish
JournalAmerican Journal of Cardiology
Volume111
Issue number8
Pages (from-to)1139-45
Number of pages7
ISSN0002-9149
DOIs
Publication statusPublished - 2013

ID: 38373746