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The Capital Region of Denmark - a part of Copenhagen University Hospital
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The EU Nickel Directive revisited--future steps towards better protection against nickel allergy

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  1. Mice with epidermal filaggrin deficiency show increased immune reactivity to nickel

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  2. Temporal changes in chromium allergy in Denmark between 2002 and 2017

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  3. Temporal changes in chromium allergy in Denmark between 2002 and 2017

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  4. Nickel deposition and penetration into the stratum corneum after short metallic nickel contact: An experimental study

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  5. Prevalence of contact allergy in the general population: A systematic review and meta-analysis

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  1. Nickel deposition and penetration into the stratum corneum after short metallic nickel contact: An experimental study

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Short contact with nickel causes allergic contact dermatitis: an experimental study

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  3. Cobalt not detected in contemporary US consumer paint colorants by cobalt indicator solution or X-ray fluorescence spectroscopy

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  4. Nickel and cobalt release from fidget spinners on the Danish market

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  5. Consumer Behaviour Among Nickel-allergic Patients

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In July 2001, the EU Nickel Directive came into full force to protect European citizens against nickel allergy and dermatitis. Prior to this intervention, Northern European governments had already begun to regulate consumer nickel exposure. According to part 2 of the EU Nickel Directive and the Danish nickel regulation, consumer items intended to be in direct and prolonged contact with the skin were not allowed to release more than 0.5 µg nickel/cm2/week. It was considered unlikely that nickel allergy would disappear altogether as a proportion of individuals reacted below the level defined by the EU Nickel Directive. Despite this, the EU Nickel Directive part 2 was expected to work as an operational limit that would sufficiently protect European consumers against nickel allergy and dermatitis. This review presents the accumulation of epidemiological studies that evaluated the possible effect of this major public health intervention. Also, it evaluates recent exposure assessment studies that have been performed using the dimethyl glyoxime test. It is concluded that the EU Nickel Directive has started to change the epidemiology of nickel allergy in Europe but it should be revisited to better protect consumers and workers since nickel allergy and dermatitis remain very frequent.
Original languageEnglish
JournalContact Dermatitis
Volume64
Issue number3
Pages (from-to)121-5
Number of pages5
ISSN0105-1873
DOIs
Publication statusPublished - 1 Mar 2011

    Research areas

  • Allergens, Consumer Product Safety, Dermatitis, Allergic Contact, European Union, Female, Humans, Nickel

ID: 32714883