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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Neurophysiological approach to disorders of peripheral nerve

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  1. Chronic inflammatory demyelinative polyneuropathy

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  2. Lyme neuroborreliosis

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  3. Preface

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  4. The surgery of peripheral nerves (including tumors)

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  5. Headache diaries and calendars

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  1. Neurologiske Sygdomme

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  2. An in vivo Mouse Model to Investigate the Effect of Local Anesthetic Nanomedicines on Axonal Conduction and Excitability

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  3. Nerve excitability in the rat forelimb: a technique to improve translational utility

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  4. Sensation, mechanoreceptor, and nerve fiber function after nerve regeneration

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  5. An oral NaV1.8 blocker improves motor function in mice completely deficient of myelin protein P0

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Disorders of the peripheral nerve system (PNS) are heterogeneous and may involve motor fibers, sensory fibers, small myelinated and unmyelinated fibers and autonomic nerve fibers, with variable anatomical distribution (single nerves, several different nerves, symmetrical affection of all nerves, plexus, or root lesions). Furthermore pathological processes may result in either demyelination, axonal degeneration or both. In order to reach an exact diagnosis of any neuropathy electrophysiological studies are crucial to obtain information about these variables. Conventional electrophysiological methods including nerve conduction studies and electromyography used in the study of patients suspected of having a neuropathy and the significance of the findings are discussed in detail and more novel and experimental methods are mentioned. Diagnostic considerations are based on a flow chart classifying neuropathies into eight categories based on mode of onset, distribution, and electrophysiological findings, and the electrophysiological characteristics in each type of neuropathy are discussed.
Original languageEnglish
Book seriesHandbook of Clinical Neurology
Volume115
Pages (from-to)81-114
Number of pages34
ISSN0072-9752
DOIs
Publication statusPublished - 2013

ID: 42521467