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Long-term results of NOPHO ALL-92 and ALL-2000 studies of childhood acute lymphoblastic leukemia

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  • K Schmiegelow
  • E Forestier
  • M Hellebostad
  • Martin Heyman Donovan
  • J Kristinsson
  • S Söderhäll
  • M Taskinen
  • Nordic Society of Paediatric Haematology and Oncology
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Analysis of 2668 children with acute lymphoblastic leukemia (ALL) treated in two successive Nordic clinical trials (Nordic Society of Paediatric Haematology and Oncology (NOPHO) ALL-92 and ALL-2000) showed that 75% of all patients are cured by first-line therapy, and 83% are long-term survivors. Improvements in systemic and intrathecal chemotherapy have reduced the use of central nervous system (CNS) irradiation to
Original languageEnglish
JournalLeukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K
Volume24
Issue number2
Pages (from-to)345-54
Number of pages10
DOIs
StatePublished - 1 Feb 2010

ID: 32249773