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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Catheter-based intervention for symptomatic patient with severe mitral regurgitation and very poor left ventricular systolic function - Safe but no room for complacency

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Many patients with left ventricular systolic dysfunction have concomitant mitral regurgitation (MR). Their symptoms and prognosis worsen with increasing severity of MR. Percutaneous MitraClip(®) can be used safely to reduce the severity of MR even in patients with advanced heart failure and is associated with improved symptoms, quality of life and exercise tolerance. However, a few patients with very poor left ventricular systolic function may experience significant haemodynamic disturbance in the peri-procedural period. We present three such patients, highlighting some of the potential problems encountered and discuss their possible pathophysiological mechanisms and safety measures.

Original languageEnglish
JournalWorld Journal of Cardiology
Volume7
Issue number11
Pages (from-to)817-21
Number of pages5
ISSN1949-8462
DOIs
Publication statusPublished - 26 Nov 2015

ID: 46181865