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The Capital Region of Denmark - a part of Copenhagen University Hospital

Evaluating automated dynamic contrast enhanced wrist 3T MRI in healthy volunteers: one-year longitudinal observational study

Research output: Contribution to journalJournal articleResearchpeer-review

  • Anshul Rastogi
  • Olga Kubassova
  • Lada V Krasnosselskaia
  • Adrian K P Lim
  • Keshthra Satchithananda
  • Mikael Boesen
  • Michael Binks
  • Joseph V Hajnal
  • Peter C Taylor
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Dynamic contrast enhanced (DCE)-MRI has great potential to provide quantitative measure of inflammatory activity in rheumatoid arthritis. There is no current benchmark to establish the stability of signal in the joints of healthy subjects when imaged with DCE-MRI longitudinally, which is crucial so as to differentiate changes induced by treatment from the inherent variability of perfusion measures. The objective of this study was to test a pixel-by-pixel parametric map based approach for analysis of DCE-MRI (Dynamika) and to investigate the variability in signal characteristics over time in healthy controls using longitudinally acquired images.
Original languageEnglish
JournalEuropean journal of radiology
Issue number8
Pages (from-to)1286-91
Number of pages6
StatePublished - Aug 2013

ID: 40463527