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Association between DPP6 polymorphism and the risk of progressive multiple sclerosis in Northern and Southern Europeans

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  1. DNA methylation regulates CHRNA7 transcription and can be modulated by valproate

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  2. Increased oxidation of RNA despite reduced mitochondrial respiration after chronic electroconvulsive stimulation of rat brain tissue

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  3. Acetazolamide lowers intracranial pressure and modulates the cerebrospinal fluid secretion pathway in healthy rats

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  4. An oral NaV1.8 blocker improves motor function in mice completely deficient of myelin protein P0

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  5. Serotonergic projections from the raphe nuclei to the subthalamic nucleus; a retrograde- and anterograde neuronal tracing study

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  1. Klinisk Neurologi og Neurokirurgi

    Research output: Book/ReportBookEducation

  2. Alcohol consumption in adolescence is associated with a lower risk of multiple sclerosis in a Danish cohort

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  3. Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility

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  4. Serum and cerebrospinal fluid neurofilament levels predict longitudinal atrophy of the cervical spinal cord in progressive MS

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  • Paola Brambilla
  • Federica Esposito
  • Eva Lindstrom
  • Melissa Sorosina
  • Giacomo Giacalone
  • Ferdinando Clarelli
  • Mariaemma Rodegher
  • Bruno Colombo
  • Lucia Moiola
  • Angelo Ghezzi
  • Ruggero Capra
  • Laura Collimedaglia
  • Gabriella Coniglio
  • Elisabeth G Celius
  • Daniela Galimberti
  • Per Soelberg Sørensen
  • Vittorio Martinelli
  • Annette B Oturai
  • Hanne F Harbo
  • Jan Hillert
  • Giancarlo Comi
  • Filippo Martinelli-Boneschi
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In this study, we investigated the role of the dipeptidyl-peptidase-6 (DPP6) gene in the etiopathogenesis of progressive forms of multiple sclerosis (PrMS). This gene emerged as a candidate gene in a genome-wide association study (GWAS) performed in an Italian sample of PrMS and controls in which two SNPs located in the gene (rs6956703 and rs11767658) showed evidence of association (nominal p-value
Original languageEnglish
JournalNeuroscience Letters
Volume530
Issue number2
Pages (from-to)155-60
Number of pages6
ISSN0304-3940
DOIs
Publication statusPublished - 2012

ID: 36727189