Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Subjective sleep quality and daytime sleepiness in late midlife and their association with age-related changes in cognition

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Assessment of diurnal melatonin, cortisol, activity, and sleep-wake cycle in patients with and without diabetic retinopathy

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Mandibular advancement device therapy for obstructive sleep apnea: a prospective study on predictors of treatment success

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Melatonin and cortisol in individuals with spinal cord injury

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Restless legs syndrome is associated with major comorbidities in a population of Danish blood donors

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Flow cytometry analysis of T-cell subsets in cerebrospinal fluid of narcolepsy type 1 patients with long-lasting disease

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. The impact of schizophrenia and intelligence on the relationship between age and brain volume

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Assessment of diurnal melatonin, cortisol, activity, and sleep-wake cycle in patients with and without diabetic retinopathy

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Disturbed sleep in cluster headache is not the result of transient processes associated with the cluster period

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Heritability of cerebral glutamate levels and their association to schizophrenia spectrum disorders: A 1 [H]-spectroscropy twin study

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Heritability of cerebral glutamate levels and their association with schizophrenia spectrum disorders: a 1[H]-spectroscopy twin study

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

In an increasingly aged population, sleep disturbances and neurodegenerative disorders have become a major public health concern. Poor sleep quality and cognitive changes are complex health problems in aging populations that are likely to be associated with increased frailty, morbidity, and mortality, and to be potential risk factors for further cognitive impairment. We aimed to evaluate whether sleep quality and excessive daytime sleepiness may be considered as early predictors of cognitive impairment.

STUDY OBJECTIVES: The objective of this study was to examine whether subjective sleep quality and daytime sleepiness are associated with cognition in middle-aged males.

PARTICIPANTS: A total of 189 healthy males born in 1953 were considered as participants for the study. Based on previous cognitive assessments, the participants were selected for the study as cognitively improved (N = 97) or cognitively impaired (N = 92).

METHODS: The Pittsburgh Sleep Quality Index and Epworth Sleepiness Scale measured subjective sleep quality and daytime sleepiness, respectively. Depressive symptoms were determined using Beck's Depression Inventory (BDI-II). A neuropsychological battery was administered to confirm group differences in cognitive functioning at the time when sleep data were collected.

RESULTS: Compared with cognitively improved males, the cognitively impaired group reported significantly lower subjective sleep quality (5.40 ± 3.81 vs. 4.39 ± 2.40, p = 0.03). Forty-one percent of the sample exhibited poor sleep quality and 15% experienced excessive daytime sleepiness. There were few correlations between sleep parameters and cognitive test performance in the combined sample.

CONCLUSION: Self-reported poor sleep quality was related to cognitive changes, whereas daytime sleepiness was not related. Our results suggest that sleep quality may be an early marker of cognitive decline in midlife.

Original languageEnglish
Article number17
JournalSleep Medicine
Volume17
Pages (from-to)165-73
Number of pages9
ISSN1389-9457
DOIs
Publication statusPublished - Jan 2016

ID: 45768199