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Assessment of Disease Activity in Large-vessel Vasculitis: Results of an International Delphi Exercise

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  • Sibel Z Aydin
  • Haner Direskeneli
  • Peter A Merkel
  • International Delphi on Disease Activity Assessment in Large-vessel Vasculitis (Bo Baslund, Mikkel Faurschou and others)
  • Bo Baslund (Member of study group)
  • Mikkel Faurschou (Member of study group)
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OBJECTIVE: To arrive at consensus for candidate outcomes for disease activity assessment in large-vessel vasculitis (LVV) in clinical trials.

METHODS: A Delphi survey including 99 items was circulated among international experts for 3 rounds.

RESULTS: Fifty-seven items were accepted for both giant cell arteritis and Takayasu arteritis. Sixty-seven percent of experts voted to have a common approach for both diseases with additional disease-specific items such as weight loss, scalp tenderness/necrosis, morning stiffness, dizziness, visual symptoms, and imaging.

CONCLUSION: This study highlights similarities and differences in experts' perspectives for assessing clinical activity in LVV and may guide a consensus-driven core set of validated outcomes.

Original languageEnglish
JournalJournal of Rheumatology
Volume44
Issue number12
Pages (from-to)1928-1932
Number of pages5
ISSN0315-162X
DOIs
Publication statusPublished - Dec 2017

    Research areas

  • Journal Article

ID: 52381766