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The Capital Region of Denmark - a part of Copenhagen University Hospital
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FSHB-211 and FSHR 2039 are associated with serum levels of follicle-stimulating hormone and antimüllerian hormone in healthy girls: a longitudinal cohort study

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  1. Associations of different molecular forms of antimüllerian hormone and biomarkers of polycystic ovary syndrome and normal women

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  2. Autotransplantation of fragmented ovarian cortical tissue: a laparoscopic demonstration

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  3. Endocrine mechanisms and assay issues in premature progesterone elevation in assisted reproductive technology

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  4. Recombinant luteinizing hormone supplementation in assisted reproductive technology: a systematic review

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  1. Characterization of Human Adrenal Steroidogenesis during Fetal Development

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  2. Populations, decreasing fertility, and reproductive health

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  3. Medium-throughput Screening Assays for Assessment of Effects on Ca2+-Signaling and Acrosome Reaction in Human Sperm

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To investigate whether genetic polymorphisms in the FSH pathway (FSHB-211 G→T and FSHR 2039 A→G) affect serum levels of FSH, antimüllerian hormone (AMH), and age at pubertal onset. FSH secretion and FSH signal transduction are enhanced in carriers of FSHB GG and FSHR AA, respectively. Furthermore, the combined genotype FSHB GG+FSHR AA is the most favorable for male gonadal function, but the effect of this genotype has never been evaluated in peripubertal females. AMH is a marker of ovarian function and is negatively correlated with FSH in prepubertal girls.
Original languageEnglish
JournalFertility and Sterility
Volume100
Issue number4
Pages (from-to)1089-1095
ISSN0015-0282
DOIs
Publication statusPublished - 11 Jul 2013

ID: 39023528