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Amplification of epidermal growth factor receptor gene in renal cell carcinoma

Research output: Contribution to journalJournal articleResearchpeer-review

  • Iman El-Hariry
  • Thomas Powles
  • Mike R Lau
  • Cora N Sternberg
  • Alain Ravaud
  • Hans von der Maase
  • Niko Zantl
  • Peter Mathias Harper
  • Frédéric Rolland
  • Bruno Audhuy
  • Friederike Barthel
  • Jean-Pascal Machiels
  • Pina Patel
  • Ernst-Dietrick Kreuser
  • Robert E Hawkins
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Expression of epidermal growth factor receptor (EGFR) may be of prognostic value in renal cell cancer (RCC). Gene amplification of EGFR was investigated in a cohort of 315 patients with advanced RCC from a previously reported randomised study. Using fluorescent in situ hybridisation, only 2 patients (0.6%) had gene amplification; therefore gene amplification is of no prognostic value in RCC.
Original languageEnglish
JournalEuropean journal of cancer (Oxford, England : 1990)
Issue number5
Pages (from-to)859-62
Number of pages4
Publication statusPublished - 1 Mar 2010

ID: 32251486