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The Capital Region of Denmark - a part of Copenhagen University Hospital

Characterization of miRNA expression in human degenerative lumbar disks

Publication: Research - peer-reviewJournal article

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microRNAs (miRNAs) are short ∼22 nucleotide RNA sequences that regulate messengerRNA translation. miRNAs have shown to play a role in synthesis of inflammatory mediators. Since inflammation play a role in intervertebral disk (IVD) degeneration, the objective was to isolate miRNA from human lumbar intervertebral disks and subsequently characterize the difference in miRNA expression between the annulus fibrosus (AF) and nucleus pulposus (NP).
Original languageEnglish
JournalConnective Tissue Research
Issue number3
Pages (from-to)197-203
Number of pages7
StatePublished - 2013

ID: 42318675