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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Infectious endocarditis caused by Escherichia coli

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  2. Mycobacterium bovis meningitis in young Nigerian-born male

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  3. Undetectable hepatitis C virus RNA during syphilis infection in two HIV/HCV-co-infected patients

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  4. Pneumocystis jirovecii pneumonia in patients with end-stage renal disease: a comparison with the general population

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  5. Antibacterial use in the Faroe Islands, Iceland, and Denmark 1999-2011

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  1. Prognostic Value of Left Atrial Functional Measures in Heart Failure With Reduced Ejection Fraction

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  2. Partial Oral versus Intravenous Antibiotic Treatment of Endocarditis

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  3. Early Versus Standard Care Invasive Examination and Treatment of Patients With Non-ST-Segment Elevation Acute Coronary Syndrome

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  4. The effect of short-course gentamicin therapy on kidney function in patients with bacteraemia-a retrospective cohort study

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Although Escherichia coli is among the most common causes of Gram-negative bacteraemia, infectious endocarditis (IE) due to this pathogen is rare. A 67-y-old male without a previous medical history presented with a new mitral regurgitation murmur and persisting E. coli bacteraemia in spite of broad-spectrum intravenous antibiotics. Transthoracic and transoesophageal echocardiography revealed a severe mitral endocarditis. E. coli DNA was identified from the mitral valve and the vegetation, and no other pathogen was found. The case was further complicated by spondylodiscitis and bilateral endophthalmitis. Extra-intestinal pathogenic E. coli (ExPEC) are able to colonize tissue outside the gastrointestinal tract and contain a variety of virulence factors that may enable the pathogens to invade and induce infections in the cardiac endothelia. In these cases echocardiography as the imaging technology is of paramount importance for the correct diagnosis and treatment.
Original languageEnglish
JournalScandinavian Journal of Infectious Diseases
Volume43
Issue number6-7
Pages (from-to)545-6
Number of pages2
ISSN0036-5548
DOIs
Publication statusPublished - 1 Jul 2011

    Research areas

  • Aged, Anti-Bacterial Agents, Bacteremia, Discitis, Echocardiography, Echocardiography, Transesophageal, Endocarditis, Endophthalmitis, Escherichia coli, Escherichia coli Infections, Humans, Infusions, Intravenous, Male, Mitral Valve

ID: 32774265