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Fat and fat-free mass at birth: air displacement plethysmography measurements on 350 Ethiopian newborns

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  1. Serum, plasma and erythrocyte membrane lipidomes in infants fed formula supplemented with bovine milk fat globule membranes

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  2. Extreme neonatal hyperbilirubinemia, acute bilirubin encephalopathy, and kernicterus spectrum disorder in children with galactosemia

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  3. NKG2D gene variation and susceptibility to viral bronchiolitis in childhood

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  4. Total brain, cortical and white matter volumes in children previously treated with glucocorticoids

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  5. Anogenital distance as a phenotypic signature through infancy

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  1. Associations between birth weight and glucose intolerance in adulthood among Greenlandic Inuit

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  2. Is the Rule of Halves framework relevant for diabetes care in Copenhagen today? A register-based cross-sectional study

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  3. Infant Feeding and its Association with Body Composition Growth Trajectories in the First 6 Months of Life: The Ethiopian iABC Birth Cohort

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  4. Trajectories of estimated GFR in patients with and without albuminuria

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  5. Incidence of diabetic eye disease among migrants: a cohort study of 100,000 adults with diabetes in Denmark

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LBW increases the risk of a number of noncommunicable diseases in adulthood. However, birth weight (BW) cannot describe variability in infant body composition (BC). Variability in fat mass (FM) and fat-free mass (FFM) at birth may be particularly important in low-income countries because they undergo nutritional transition. There is a need for data on birth BC and its predictors from low-income countries in transition. We assessed absolute FM and FFM at birth and examined the role of gender, parity, GA, and LBW as predictors of birth BC. FM and FFM were assessed within 48 h of birth on 350 Ethiopian newborns using air displacement plethysmography (ADP). Female gender and being an infant of primi- or secundiparous mothers predicted lower BW and lower birth FFM but not FM, compared with male gender and infants of multiparous mothers, respectively. There was a positive linear relationship between BW and relative amount of FM for boys and girls. This study presents reference data on birth FM and FFM from a low-income setting and provides background for further longitudinal mapping of the relationship between fetal BC, childhood growth, and adult disease.

Original languageEnglish
JournalPediatric Research
Volume70
Issue number5
Pages (from-to)501-6
Number of pages6
ISSN0031-3998
DOIs
Publication statusPublished - Nov 2011

    Research areas

  • Adipose Tissue, Birth Order, Birth Weight, Body Composition, Ethiopia, Female, Humans, Infant, Newborn, Linear Models, Male, Plethysmography, Sex Factors, Journal Article, Research Support, Non-U.S. Gov't

ID: 51755384