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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Percutaneous penetration characteristics and release kinetics of contact allergens encapsulated in ethosomes

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Encapsulating contact allergens in liposomes, ethosomes, and polycaprolactone may affect their sensitizing properties

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Temporal changes in chromium allergy in Denmark between 2002 and 2017

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Nickel deposition and penetration into the stratum corneum after short metallic nickel contact: An experimental study

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Prevalence of contact allergy in the general population: A systematic review and meta-analysis

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Occupational allergic contact dermatitis caused by cobalt in machine oil

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. The European baseline series and recommended additions: 2019

    Research output: Contribution to journalReviewResearchpeer-review

  • Jakob Torp Madsen
  • Stefan Vogel
  • Jeanne Duus Johansen
  • Jens Ahm Sørensen
  • Klaus Ejner Andersen
  • Jesper Bo Nielsen
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Formulation of the contact allergens dinitrochlorobenzene and isoeugenol in ethanolic liposomes (ethosomes) increases their sensitizing properties in the local lymph node assay compared with an ethanol-water formulation of the allergens. Likewise, isoeugenol and methyldibromo-glutaronitrile formulated in ethosomes enhanced the patch test reactions in sensitized human volunteers. The relationship between the percutaneous penetration/absorption and sensitization/elicitation phases of contact allergy is not well elucidated.
Original languageEnglish
JournalCutaneous and Ocular Toxicology
Volume30
Issue number1
Pages (from-to)38-44
Number of pages7
ISSN1556-9527
DOIs
Publication statusPublished - 1 Mar 2011

    Research areas

  • Administration, Cutaneous, Adult, Allergens, Chemistry, Pharmaceutical, Dermatitis, Allergic Contact, Dinitrochlorobenzene, Drug Compounding, Ethanol, Eugenol, Female, Humans, Immunization, Irritants, Liposomes, Skin, Skin Absorption

ID: 32676243