ICG angiography in immediate and delayed autologous breast reconstructions: peroperative evaluation and postoperative outcomes

Toke Alstrup, Bekka O Christensen, Tine Engberg Damsgaard


Postoperative complications in patients undergoing autologous breast reconstruction should be kept at the lowest possible level. Optimization of autologous breast reconstruction, especially techniques that can identify tissue perfusion and ischemia, will greatly benefit the patients and consequently society. Hence, the aim of this study was to evaluate the complication rates for autologous pedicle flap breast reconstructions, with and without the use of ICG-angiography. A single-institution retrospective review of mastectomy patients was performed. A total of 230 cases who underwent immediate or delayed, unilateral or bilateral pedicle autologous flap breast reconstruction between January 2013 and September 2016 was reviewed. Complication rates in the ICG-angiography and clinical assessment group were evaluated and compared. A total of 191 cases were identified of which 77 were evaluated with ICG-angiography, and 114 were evaluated clinically. There was no significant difference in overall complication rates between the two groups (ICG-angiography, 36.4%; Clinical assessment, 37.7%; p = .88). No significant difference was observed when stratifying for major or minor complications. However, when stratifying for the timing of the reconstruction, the rate of major complications was significantly lower in the ICG-angiography group (ICG-angiography, 0%; Clinical assessment 23.3%; p = .039). BMI was significantly associated with increased risk of minor complications (p = .018), whereas there was no correlation to age, prior smoking, chemotherapy, radiation, diabetes, or hypertension. Our study found that use of ICG-angiography was associated with a significant decrease in the rate of major complications for immediate autologous reconstructions.

Original languageEnglish
JournalJournal of Plastic Surgery and Hand Surgery
Issue number5
Pages (from-to)307-311
Number of pages5
Publication statusPublished - Oct 2018
Externally publishedYes


  • Angiography
  • Body Mass Index
  • Breast/blood supply
  • Breast Neoplasms/surgery
  • Coloring Agents
  • Female
  • Humans
  • Indocyanine Green
  • Intraoperative Care
  • Ischemia/prevention & control
  • Mammaplasty
  • Mastectomy
  • Middle Aged
  • Postoperative Complications
  • Retrospective Studies
  • Surgical Flaps/blood supply
  • Time-to-Treatment


Dive into the research topics of 'ICG angiography in immediate and delayed autologous breast reconstructions: peroperative evaluation and postoperative outcomes'. Together they form a unique fingerprint.

Cite this