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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Hypokalemia and rhabdomyolysis

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Horwitz, Henrik ; Woeien, Vidar A ; Petersen, Linda Wiuff ; Jimenez-Solem, Espen. / Hypokalemia and rhabdomyolysis. In: Journal of pharmacology & pharmacotherapeutics. 2015 ; Vol. 6, No. 2. pp. 98-9.

Bibtex

@article{de889c9284b041b8bd938fe8ecc026f7,
title = "Hypokalemia and rhabdomyolysis",
abstract = "The adverse drug event manager of the Capital Region of Denmark received a report of a 65-year-old male with type II diabetes and long-lasting treatment with indapamide. In addition, he had a history of a high consumption of licorice. For 2 weeks, the patient suffered from myalgia, which the general practitioner suspected to be polymyalgia rheumatica and referred him to the hospital. Initial blood samples revealed a reduced potassium concentration of 1.5 mmol/L (reference value: 6.6-4.6 mmol/L) and an elevated creatine kinase of 18,400 IU/L (reference value: 40-280 IU/L). We believe that the patient developed rhabdomyolysis due to severe hypokalemia, possibly induced by a pharmacodynamic interaction between licorice and indapamide. ",
author = "Henrik Horwitz and Woeien, {Vidar A} and Petersen, {Linda Wiuff} and Espen Jimenez-Solem",
year = "2015",
month = may,
day = "15",
doi = "10.4103/0976-500X.155488",
language = "English",
volume = "6",
pages = "98--9",
journal = "Journal of pharmacology & pharmacotherapeutics",
issn = "0976-500X",
publisher = "Wolters Kluwer Medknow Publications",
number = "2",

}

RIS

TY - JOUR

T1 - Hypokalemia and rhabdomyolysis

AU - Horwitz, Henrik

AU - Woeien, Vidar A

AU - Petersen, Linda Wiuff

AU - Jimenez-Solem, Espen

PY - 2015/5/15

Y1 - 2015/5/15

N2 - The adverse drug event manager of the Capital Region of Denmark received a report of a 65-year-old male with type II diabetes and long-lasting treatment with indapamide. In addition, he had a history of a high consumption of licorice. For 2 weeks, the patient suffered from myalgia, which the general practitioner suspected to be polymyalgia rheumatica and referred him to the hospital. Initial blood samples revealed a reduced potassium concentration of 1.5 mmol/L (reference value: 6.6-4.6 mmol/L) and an elevated creatine kinase of 18,400 IU/L (reference value: 40-280 IU/L). We believe that the patient developed rhabdomyolysis due to severe hypokalemia, possibly induced by a pharmacodynamic interaction between licorice and indapamide.

AB - The adverse drug event manager of the Capital Region of Denmark received a report of a 65-year-old male with type II diabetes and long-lasting treatment with indapamide. In addition, he had a history of a high consumption of licorice. For 2 weeks, the patient suffered from myalgia, which the general practitioner suspected to be polymyalgia rheumatica and referred him to the hospital. Initial blood samples revealed a reduced potassium concentration of 1.5 mmol/L (reference value: 6.6-4.6 mmol/L) and an elevated creatine kinase of 18,400 IU/L (reference value: 40-280 IU/L). We believe that the patient developed rhabdomyolysis due to severe hypokalemia, possibly induced by a pharmacodynamic interaction between licorice and indapamide.

U2 - 10.4103/0976-500X.155488

DO - 10.4103/0976-500X.155488

M3 - Journal article

C2 - 25969658

VL - 6

SP - 98

EP - 99

JO - Journal of pharmacology & pharmacotherapeutics

JF - Journal of pharmacology & pharmacotherapeutics

SN - 0976-500X

IS - 2

ER -

ID: 66836156