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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Hypertensive nephropathy is associated with an increased risk of myeloma, skin, and renal cancer

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  1. Several Conventional Risk Markers Suggesting Presence of Albuminuria Are Weak Among Rural Africans With Hypertension

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  2. Discrepancy between tonometric ambulatory and cuff-based office blood pressure measurements in patients with type 1 diabetes

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  3. Diagnostic Thresholds for Ambulatory Blood Pressure Moving Lower: A Review Based on a Meta-analysis - Clinical Implications.

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  1. FGF23 in hemodialysis patients is associated with left ventricular hypertrophy and reduced ejection fraction

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  2. Quantification of cancer risk in glomerulonephritis

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Previous studies suggest an increased cancer risk in hypertension. Patients with hypertensive nephropathy have not been studied. A national registry study was performed to assess the presence and size of this association. Clinical data and cancer diagnoses for all patients with biopsy-proven hypertensive nephropathy between 1985 and 2015 in Denmark were extracted from four national registries and compared with age- and sex-adjusted national cancer rates. The risk of cancer was twice the background population. It was raised for renal cancer (odds ratio 10.4), myeloma (13.2), skin cancer (7.9), and other/unspecified (1.8). No increase in incidence was seen until 1 year before renal biopsy and then rose rapidly. It was again normal 5 years after biopsy. Hypertensive nephropathy is associated with an increased risk of myeloma, skin, renal, and other cancers. Screening of patients with hypertensive nephropathy, in the presence of reduced renal function or significant proteinuria, may be indicated.

Original languageEnglish
JournalJournal of Clinical Hypertension
Volume21
Issue number6
Pages (from-to)786-791
Number of pages6
ISSN1524-6175
DOIs
Publication statusPublished - Jun 2019

ID: 59102691