Hydroxyethyl starch 130/0.42 versus Ringer's acetate in severe sepsis

Anders Perner, Nicolai Haase, Anne B Guttormsen, Jyrki Tenhunen, Gudmundur Klemenzson, Anders Åneman, Kristian R Madsen, Morten H Møller, Jeanie M Elkjær, Lone M Poulsen, Asger Bendtsen, Robert Winding, Morten Steensen, Pawel Berezowicz, Peter Søe-Jensen, Morten Bestle, Kristian Strand, Jørgen Wiis, Jonathan O White, Klaus J ThornbergLars Quist, Jonas Nielsen, Lasse H Andersen, Lars B Holst, Katrin Thormar, Anne-Lene Kjældgaard, Maria L Fabritius, Frederik Mondrup, Frank C Pott, Thea P Møller, Per Winkel, Jørn Wetterslev, 6S Trial Group

1498 Citations (Scopus)

Abstract

Hydroxyethyl starch (HES) [corrected] is widely used for fluid resuscitation in intensive care units (ICUs), but its safety and efficacy have not been established in patients with severe sepsis.
Original languageEnglish
JournalNew England Journal of Medicine
Volume367
Issue number2
Pages (from-to)124-34
Number of pages11
ISSN0028-4793
DOIs
Publication statusPublished - 2012

Keywords

  • Aged
  • Double-Blind Method
  • Female
  • Fluid Therapy
  • Hemorrhage
  • Hetastarch
  • Humans
  • Intention to Treat Analysis
  • Isotonic Solutions
  • Kidney Failure, Chronic
  • Male
  • Middle Aged
  • Renal Replacement Therapy
  • Sepsis

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