Human leucocyte antigens in patients with alcoholic liver cirrhosis

C Gluud; J Aldershvile; O Dietrichson; F Hardt; K Iversen; E Juhl; J O Nielsen; L P Ryder; P Skinhøj; A Svejgaard

Human leucocyte antigens in patients with alcoholic liver cirrhosis

C Gluud, J Aldershvile, O Dietrichson, F Hardt, K Iversen, E Juhl, J O Nielsen, L P Ryder, P Skinhøj, A Svejgaard

Copenhagen Trial Unit

21 Citations (Scopus)

Abstract

No significant differences in the frequencies of HLA-B8, -B40, and other HLA-A, -B, and -C phenotypes were found among patients with histologically verified alcoholic cirrhosis compared with normal controls when the p values were multiplied by the number of comparisons. This was found both in the present study of 45 patients and in the combined data of this and three other similar studies. However, these findings do not rule out that alcoholic cirrhosis might be associated with HLA factors (for example. HLA-D/DR antigens) controlling immune responses.

Original language	English
Journal	Scandinavian Journal of Gastroenterology
Volume	15
Issue number	3
Pages (from-to)	337-41
Number of pages	5
ISSN	0036-5521
Publication status	Published - 1980

Keywords

Adult
Aged
Cytotoxicity Tests, Immunologic
Denmark
Female
Gene Frequency
HLA Antigens
Humans
Leukocytes
Liver Cirrhosis, Alcoholic
Male
Middle Aged

Cite this

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title = "Human leucocyte antigens in patients with alcoholic liver cirrhosis",

abstract = "No significant differences in the frequencies of HLA-B8, -B40, and other HLA-A, -B, and -C phenotypes were found among patients with histologically verified alcoholic cirrhosis compared with normal controls when the p values were multiplied by the number of comparisons. This was found both in the present study of 45 patients and in the combined data of this and three other similar studies. However, these findings do not rule out that alcoholic cirrhosis might be associated with HLA factors (for example. HLA-D/DR antigens) controlling immune responses.",

keywords = "Adult, Aged, Cytotoxicity Tests, Immunologic, Denmark, Female, Gene Frequency, HLA Antigens, Humans, Leukocytes, Liver Cirrhosis, Alcoholic, Male, Middle Aged",

author = "C Gluud and J Aldershvile and O Dietrichson and F Hardt and K Iversen and E Juhl and Nielsen, \{J O\} and Ryder, \{L P\} and P Skinh{\o}j and A Svejgaard",

year = "1980",

language = "English",

volume = "15",

pages = "337--41",

journal = "Scandinavian Journal of Gastroenterology",

issn = "0036-5521",

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TY - JOUR

T1 - Human leucocyte antigens in patients with alcoholic liver cirrhosis

AU - Gluud, C

AU - Aldershvile, J

AU - Dietrichson, O

AU - Hardt, F

AU - Iversen, K

AU - Juhl, E

AU - Nielsen, J O

AU - Ryder, L P

AU - Skinhøj, P

AU - Svejgaard, A

PY - 1980

Y1 - 1980

N2 - No significant differences in the frequencies of HLA-B8, -B40, and other HLA-A, -B, and -C phenotypes were found among patients with histologically verified alcoholic cirrhosis compared with normal controls when the p values were multiplied by the number of comparisons. This was found both in the present study of 45 patients and in the combined data of this and three other similar studies. However, these findings do not rule out that alcoholic cirrhosis might be associated with HLA factors (for example. HLA-D/DR antigens) controlling immune responses.

AB - No significant differences in the frequencies of HLA-B8, -B40, and other HLA-A, -B, and -C phenotypes were found among patients with histologically verified alcoholic cirrhosis compared with normal controls when the p values were multiplied by the number of comparisons. This was found both in the present study of 45 patients and in the combined data of this and three other similar studies. However, these findings do not rule out that alcoholic cirrhosis might be associated with HLA factors (for example. HLA-D/DR antigens) controlling immune responses.

KW - Adult

KW - Aged

KW - Cytotoxicity Tests, Immunologic

KW - Denmark

KW - Female

KW - Gene Frequency

KW - HLA Antigens

KW - Humans

KW - Leukocytes

KW - Liver Cirrhosis, Alcoholic

KW - Male

KW - Middle Aged

UR - https://www.scopus.com/pages/publications/0018824389

M3 - Journal article

C2 - 7433893

SN - 0036-5521

VL - 15

SP - 337

EP - 341

JO - Scandinavian Journal of Gastroenterology

JF - Scandinavian Journal of Gastroenterology

IS - 3

ER -

Human leucocyte antigens in patients with alcoholic liver cirrhosis

Abstract

Keywords

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