Human β-defensin-2 as a marker for disease severity and skin barrier properties in atopic dermatitis

M-L Clausen; J M Jungersted; P S Andersen; H-C Slotved; Karen Krogfelt; T Agner

doi:10.1111/bjd.12419

Human β-defensin-2 as a marker for disease severity and skin barrier properties in atopic dermatitis

M-L Clausen, J M Jungersted, P S Andersen, H-C Slotved, Karen Krogfelt, T Agner

Department of Dermatology

54 Citations (Scopus)

Abstract

Skin infections related to disrupted antimicrobial defence are a common problem in atopic dermatitis (AD). Altered levels of antimicrobial peptides, including human β-defensin (hBD)-2, have been reported in AD skin, and a link to impaired barrier function has been suggested.

Original language	English
Journal	British Journal of Dermatology
Volume	169
Issue number	3
Pages (from-to)	587-93
Number of pages	7
ISSN	0007-0963
DOIs	https://doi.org/10.1111/bjd.12419
Publication status	Published - Sept 2013

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10.1111/bjd.12419

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title = "Human β-defensin-2 as a marker for disease severity and skin barrier properties in atopic dermatitis",

abstract = "Skin infections related to disrupted antimicrobial defence are a common problem in atopic dermatitis (AD). Altered levels of antimicrobial peptides, including human β-defensin (hBD)-2, have been reported in AD skin, and a link to impaired barrier function has been suggested.",

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AU - Clausen, M-L

AU - Jungersted, J M

AU - Andersen, P S

AU - Slotved, H-C

AU - Krogfelt, Karen

AU - Agner, T

PY - 2013/9

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N2 - Skin infections related to disrupted antimicrobial defence are a common problem in atopic dermatitis (AD). Altered levels of antimicrobial peptides, including human β-defensin (hBD)-2, have been reported in AD skin, and a link to impaired barrier function has been suggested.

AB - Skin infections related to disrupted antimicrobial defence are a common problem in atopic dermatitis (AD). Altered levels of antimicrobial peptides, including human β-defensin (hBD)-2, have been reported in AD skin, and a link to impaired barrier function has been suggested.

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U2 - 10.1111/bjd.12419

DO - 10.1111/bjd.12419

M3 - Journal article

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JO - British Journal of Dermatology

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Human β-defensin-2 as a marker for disease severity and skin barrier properties in atopic dermatitis

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