HIV-1-infected individuals in antiretroviral therapy react specifically with polyfunctional T-cell responses to Gag p24

Lea Brandt, Thomas Benfield, Gitte Kronborg, Jan Gerstoft, Anders Fomsgaard, Ingrid Karlsson

8 Citations (Scopus)

Abstract

Still no effective HIV-1 prophylactic or therapeutic vaccines are available. However, as the proportion of HIV-1-infected individuals on antiretroviral treatment is increasing, knowledge about the residual immune response is important for the possible development of an HIV-1 vaccine.
Original languageEnglish
JournalJournal of acquired immune deficiency syndromes (1999)
Volume63
Issue number4
Pages (from-to)418-27
Number of pages10
ISSN1525-4135
DOIs
Publication statusPublished - 1 Aug 2013

Keywords

  • Antiretroviral Therapy, Highly Active
  • Antiviral Agents
  • CD4 Lymphocyte Count
  • CD4-Positive T-Lymphocytes
  • CD8-Positive T-Lymphocytes
  • Cells, Cultured
  • Cytokines
  • Female
  • HIV Core Protein p24
  • HIV Infections
  • HIV Integrase
  • HIV-1
  • HLA Antigens
  • Humans
  • Male
  • RNA, Viral
  • Viral Load
  • nef Gene Products, Human Immunodeficiency Virus

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