Histopathology of plaque rupture

Hanne Berg Ravn; Erling Falk

doi:10.1016/s0733-8651(05)70073-4

Histopathology of plaque rupture

Hanne Berg Ravn, Erling Falk

44 Citations (Scopus)

Abstract

Plaque disruption occurs during the development of atherosclerotic lesions. During certain circumstances it may result in thrombosis and subsequent development of acute coronary syndromes. Several characteristics of the plaque appear to be associated with plaque disruption, including a large lipid rich core, superficial plaque inflammation, and a thin fibrous cap. The importance of these and other plaque components are discussed in this article.

Original language	English
Journal	Clinical Cardiology
Volume	17
Issue number	2
Pages (from-to)	263-70, vii
Number of pages	7
ISSN	0733-8651
DOIs	https://doi.org/10.1016/s0733-8651(05)70073-4
Publication status	Published - 1999
Externally published	Yes

Keywords

Biomechanical Phenomena
Coronary Artery Disease/blood
Coronary Vessels/pathology
Disease Progression
Fibrinogen/analysis
Humans
Immunochemistry
Metalloendopeptidases/analysis
Rupture, Spontaneous

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10.1016/s0733-8651(05)70073-4

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title = "Histopathology of plaque rupture",

abstract = "Plaque disruption occurs during the development of atherosclerotic lesions. During certain circumstances it may result in thrombosis and subsequent development of acute coronary syndromes. Several characteristics of the plaque appear to be associated with plaque disruption, including a large lipid rich core, superficial plaque inflammation, and a thin fibrous cap. The importance of these and other plaque components are discussed in this article.",

keywords = "Biomechanical Phenomena, Coronary Artery Disease/blood, Coronary Vessels/pathology, Disease Progression, Fibrinogen/analysis, Humans, Immunochemistry, Metalloendopeptidases/analysis, Rupture, Spontaneous",

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AB - Plaque disruption occurs during the development of atherosclerotic lesions. During certain circumstances it may result in thrombosis and subsequent development of acute coronary syndromes. Several characteristics of the plaque appear to be associated with plaque disruption, including a large lipid rich core, superficial plaque inflammation, and a thin fibrous cap. The importance of these and other plaque components are discussed in this article.

KW - Biomechanical Phenomena

KW - Coronary Artery Disease/blood

KW - Coronary Vessels/pathology

KW - Disease Progression

KW - Fibrinogen/analysis

KW - Humans

KW - Immunochemistry

KW - Metalloendopeptidases/analysis

KW - Rupture, Spontaneous

U2 - 10.1016/s0733-8651(05)70073-4

DO - 10.1016/s0733-8651(05)70073-4

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SN - 0733-8651

VL - 17

SP - 263-70, vii

JO - Clinical Cardiology

JF - Clinical Cardiology

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ER -

Histopathology of plaque rupture

Abstract

Keywords

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