Higher plasma soluble Receptor for Advanced Glycation End Products (sRAGE) levels are associated with incident cardiovascular disease and all-cause mortality in type 1 diabetes: a 12-year follow-up study

Johanna W M Nin; Anders Jorsal; Isabel Maria Merces Ferreira; Casper G Schalkwijk; Martin H Prins; Hans-Henrik Parving; Lise Tarnow; Peter Rossing; Coen D A Stehouwer

doi:10.2337/db09-1509

Higher plasma soluble Receptor for Advanced Glycation End Products (sRAGE) levels are associated with incident cardiovascular disease and all-cause mortality in type 1 diabetes: a 12-year follow-up study

Johanna W M Nin
, Anders Jorsal
, Isabel Maria Merces Ferreira
, Casper G Schalkwijk
, Martin H Prins
, Hans-Henrik Parving
, Lise Tarnow
, Peter Rossing
, Coen D A Stehouwer

118 Citations (Scopus)

Abstract

To investigate the associations of plasma levels of soluble receptor for advanced glycation end products (sRAGE) with incident cardiovascular disease (CVD) and all-cause mortality in type 1 diabetes and the extent to which any such associations could be explained by endothelial and renal dysfunction, low-grade inflammation, arterial stiffness, and advanced glycation end products (AGEs).

Original language	English
Journal	Diabetes
Volume	59
Issue number	8
Pages (from-to)	2027-32
Number of pages	6
DOIs	https://doi.org/10.2337/db09-1509
Publication status	Published - 1 Aug 2010

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10.2337/db09-1509

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Nin, J. W. M., Jorsal, A., Merces Ferreira, I. M., Schalkwijk, C. G., Prins, M. H., Parving, H.-H., Tarnow, L., Rossing, P., & Stehouwer, C. D. A. (2010). Higher plasma soluble Receptor for Advanced Glycation End Products (sRAGE) levels are associated with incident cardiovascular disease and all-cause mortality in type 1 diabetes: a 12-year follow-up study. Diabetes, 59(8), 2027-32. https://doi.org/10.2337/db09-1509

Higher plasma soluble Receptor for Advanced Glycation End Products (sRAGE) levels are associated with incident cardiovascular disease and all-cause mortality in type 1 diabetes: a 12-year follow-up study. / Nin, Johanna W M; Jorsal, Anders; Merces Ferreira, Isabel Maria et al.
In: Diabetes, Vol. 59, No. 8, 01.08.2010, p. 2027-32.

Research output: Contribution to journal › Journal article › Research › peer-review

Nin, JWM, Jorsal, A, Merces Ferreira, IM, Schalkwijk, CG, Prins, MH, Parving, H-H, Tarnow, L, Rossing, P & Stehouwer, CDA 2010, 'Higher plasma soluble Receptor for Advanced Glycation End Products (sRAGE) levels are associated with incident cardiovascular disease and all-cause mortality in type 1 diabetes: a 12-year follow-up study', Diabetes, vol. 59, no. 8, pp. 2027-32. https://doi.org/10.2337/db09-1509

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abstract = "To investigate the associations of plasma levels of soluble receptor for advanced glycation end products (sRAGE) with incident cardiovascular disease (CVD) and all-cause mortality in type 1 diabetes and the extent to which any such associations could be explained by endothelial and renal dysfunction, low-grade inflammation, arterial stiffness, and advanced glycation end products (AGEs).",

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AU - Merces Ferreira, Isabel Maria

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AU - Prins, Martin H

AU - Parving, Hans-Henrik

AU - Tarnow, Lise

AU - Rossing, Peter

AU - Stehouwer, Coen D A

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AB - To investigate the associations of plasma levels of soluble receptor for advanced glycation end products (sRAGE) with incident cardiovascular disease (CVD) and all-cause mortality in type 1 diabetes and the extent to which any such associations could be explained by endothelial and renal dysfunction, low-grade inflammation, arterial stiffness, and advanced glycation end products (AGEs).

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Higher plasma soluble Receptor for Advanced Glycation End Products (sRAGE) levels are associated with incident cardiovascular disease and all-cause mortality in type 1 diabetes: a 12-year follow-up study

Abstract

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