Higher plasma high-mobility group box 1 levels are associated with incident cardiovascular disease and all-cause mortality in type 1 diabetes: a 12 year follow-up study

J W M Nin; I Ferreira; C G Schalkwijk; Anders Jorsal; M H Prins; H-H Parving; Lise Tarnow; Pia Rossing; C D A Stehouwer

doi:10.1007/s00125-012-2622-1

Higher plasma high-mobility group box 1 levels are associated with incident cardiovascular disease and all-cause mortality in type 1 diabetes: a 12 year follow-up study

J W M Nin, I Ferreira, C G Schalkwijk, Anders Jorsal, M H Prins, H-H Parving, Lise Tarnow, Pia Rossing, C D A Stehouwer

29 Citations (Scopus)

Abstract

This study aimed to investigate the associations of plasma levels of the pro-inflammatory cytokine high-mobility group box 1 (HMGB1) with incident cardiovascular disease (CVD) and all-cause mortality in patients with type 1 diabetes.

Original language	English
Journal	Diabetologia
Volume	55
Issue number	9
Pages (from-to)	2489-93
Number of pages	5
ISSN	0012-186X
DOIs	https://doi.org/10.1007/s00125-012-2622-1
Publication status	Published - 2012

Keywords

Albuminuria
Biological Markers
Cardiovascular Diseases
Denmark
Diabetes Mellitus, Type 1
Diabetic Angiopathies
Diabetic Nephropathies
Female
Follow-Up Studies
HMGB1 Protein
Humans
Incidence
Inflammation
Male
Netherlands
Prospective Studies
Risk Factors

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10.1007/s00125-012-2622-1

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Nin, J. W. M., Ferreira, I., Schalkwijk, C. G., Jorsal, A., Prins, M. H., Parving, H.-H., Tarnow, L., Rossing, P., & Stehouwer, C. D. A. (2012). Higher plasma high-mobility group box 1 levels are associated with incident cardiovascular disease and all-cause mortality in type 1 diabetes: a 12 year follow-up study. Diabetologia, 55(9), 2489-93. https://doi.org/10.1007/s00125-012-2622-1

Nin, JWM, Ferreira, I, Schalkwijk, CG, Jorsal, A, Prins, MH, Parving, H-H, Tarnow, L, Rossing, P & Stehouwer, CDA 2012, 'Higher plasma high-mobility group box 1 levels are associated with incident cardiovascular disease and all-cause mortality in type 1 diabetes: a 12 year follow-up study', Diabetologia, vol. 55, no. 9, pp. 2489-93. https://doi.org/10.1007/s00125-012-2622-1

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abstract = "This study aimed to investigate the associations of plasma levels of the pro-inflammatory cytokine high-mobility group box 1 (HMGB1) with incident cardiovascular disease (CVD) and all-cause mortality in patients with type 1 diabetes.",

keywords = "Albuminuria, Biological Markers, Cardiovascular Diseases, Denmark, Diabetes Mellitus, Type 1, Diabetic Angiopathies, Diabetic Nephropathies, Female, Follow-Up Studies, HMGB1 Protein, Humans, Incidence, Inflammation, Male, Netherlands, Prospective Studies, Risk Factors",

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AU - Nin, J W M

AU - Ferreira, I

AU - Schalkwijk, C G

AU - Jorsal, Anders

AU - Prins, M H

AU - Parving, H-H

AU - Tarnow, Lise

AU - Rossing, Pia

AU - Stehouwer, C D A

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KW - Albuminuria

KW - Biological Markers

KW - Cardiovascular Diseases

KW - Denmark

KW - Diabetes Mellitus, Type 1

KW - Diabetic Angiopathies

KW - Diabetic Nephropathies

KW - Female

KW - Follow-Up Studies

KW - HMGB1 Protein

KW - Humans

KW - Incidence

KW - Inflammation

KW - Male

KW - Netherlands

KW - Prospective Studies

KW - Risk Factors

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SP - 2489

EP - 2493

JO - Diabetologia

JF - Diabetologia

IS - 9

ER -

Higher plasma high-mobility group box 1 levels are associated with incident cardiovascular disease and all-cause mortality in type 1 diabetes: a 12 year follow-up study

Abstract

Keywords

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