Higher occurrence of childhood cancer in families with germline mutations in BRCA2, MMR and CDKN2A genes.

Susanne Magnusson; Ake Borg; Ulf Kristoffersson; Mef Nilbert; Thomas Wiebe; Håkan Olsson

doi:10.1007/s10689-008-9195-7

Higher occurrence of childhood cancer in families with germline mutations in BRCA2, MMR and CDKN2A genes.

Susanne Magnusson, Ake Borg, Ulf Kristoffersson, Mef Nilbert, Thomas Wiebe, Håkan Olsson

Department of Clinical Research

33 Citations (Scopus)

Abstract

The contribution of hereditary factors for development of childhood tumors is limited to some few known syndromes associated with predominance of tumors in childhood. Occurrence of childhood tumors in hereditary cancer syndromes such as BRCA1/2 associated breast and ovarian cancer, DNA-mismatch repair (MMR) genes associated hereditary non polyposis colorectal cancer and CDKN2A associated familial malignant melanoma are very little studied. Herein we report the prevalence of childhood tumors (diagnosed

Original language	English
Journal	Familial Cancer
Volume	7
Issue number	4
Pages (from-to)	331-7
Number of pages	6
ISSN	1389-9600
DOIs	https://doi.org/10.1007/s10689-008-9195-7
Publication status	Published - 2008

Access to Document

10.1007/s10689-008-9195-7

Cite this

@article{a19d453c432d478fb6d0187e67f71d9d,

title = "Higher occurrence of childhood cancer in families with germline mutations in BRCA2, MMR and CDKN2A genes.",

abstract = "The contribution of hereditary factors for development of childhood tumors is limited to some few known syndromes associated with predominance of tumors in childhood. Occurrence of childhood tumors in hereditary cancer syndromes such as BRCA1/2 associated breast and ovarian cancer, DNA-mismatch repair (MMR) genes associated hereditary non polyposis colorectal cancer and CDKN2A associated familial malignant melanoma are very little studied. Herein we report the prevalence of childhood tumors (diagnosed",

author = "Susanne Magnusson and Ake Borg and Ulf Kristoffersson and Mef Nilbert and Thomas Wiebe and H{\aa}kan Olsson",

year = "2008",

doi = "10.1007/s10689-008-9195-7",

language = "English",

volume = "7",

pages = "331--7",

journal = "Familial Cancer",

issn = "1389-9600",

publisher = "Springer Science and Business Media B.V.",

number = "4",

}

TY - JOUR

T1 - Higher occurrence of childhood cancer in families with germline mutations in BRCA2, MMR and CDKN2A genes.

AU - Magnusson, Susanne

AU - Borg, Ake

AU - Kristoffersson, Ulf

AU - Nilbert, Mef

AU - Wiebe, Thomas

AU - Olsson, Håkan

PY - 2008

Y1 - 2008

N2 - The contribution of hereditary factors for development of childhood tumors is limited to some few known syndromes associated with predominance of tumors in childhood. Occurrence of childhood tumors in hereditary cancer syndromes such as BRCA1/2 associated breast and ovarian cancer, DNA-mismatch repair (MMR) genes associated hereditary non polyposis colorectal cancer and CDKN2A associated familial malignant melanoma are very little studied. Herein we report the prevalence of childhood tumors (diagnosed

AB - The contribution of hereditary factors for development of childhood tumors is limited to some few known syndromes associated with predominance of tumors in childhood. Occurrence of childhood tumors in hereditary cancer syndromes such as BRCA1/2 associated breast and ovarian cancer, DNA-mismatch repair (MMR) genes associated hereditary non polyposis colorectal cancer and CDKN2A associated familial malignant melanoma are very little studied. Herein we report the prevalence of childhood tumors (diagnosed

UR - https://www.scopus.com/pages/publications/55949137903

U2 - 10.1007/s10689-008-9195-7

DO - 10.1007/s10689-008-9195-7

M3 - Journal article

C2 - 18481196

SN - 1389-9600

VL - 7

SP - 331

EP - 337

JO - Familial Cancer

JF - Familial Cancer

IS - 4

ER -

Higher occurrence of childhood cancer in families with germline mutations in BRCA2, MMR and CDKN2A genes.

Abstract

Access to Document

Other files and links

Fingerprint

Cite this