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High prevalence of Clostridium difficile diarrhoea during intensive chemotherapy for disseminated germ cell cancer

H Nielsen, G Daugaard, M Tvede, B Bruun

25 Citations (Scopus)

Abstract

A prospective, consecutive study of the aetiology of treatment-associated diarrhoea was conducted in 25 patients with disseminated germ cell cancer treated with intensive chemotherapy. Clostridium difficile was isolated in 45% of the diarrhoea episodes, which makes this species the most important bacterial pathogen in the development of clinically significant diarrhoea in this group of immunocompromised patients.

Original languageEnglish
JournalBritish Journal of Cancer
Volume66
Issue number4
Pages (from-to)666-7
Number of pages2
ISSN0007-0920
DOIs
Publication statusPublished - Oct 1992
Externally publishedYes

Keywords

  • Antineoplastic Combined Chemotherapy Protocols/administration & dosage
  • Bleomycin/administration & dosage
  • Cisplatin/administration & dosage
  • Clostridioides difficile/isolation & purification
  • Diarrhea/drug therapy
  • Etoposide/administration & dosage
  • Humans
  • Immunocompromised Host
  • Neoplasms, Germ Cell and Embryonal/drug therapy
  • Prevalence
  • Prospective Studies

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