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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Hepcidin levels are low during pregnancy and increase around delivery in women without iron deficiency - a prospective cohort study

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OBJECTIVE: To investigate hepcidin during pregnancy, delivery and postpartum in women with sufficient iron supplementation.

METHODS: Hepcidin was measured using LC-MS spectroscopy in 37 women during pregnancy, delivery and postpartum period in this longitudinal study.

RESULTS: Hepcidin was low during pregnancy and increased at delivery and postpartum. No correlations with inflammatory markers or iron metabolism were observed during pregnancy; at delivery a correlation with inflammatory markers was observed.

CONCLUSION: During pregnancy, in women with sufficient iron supplementation, hepcidin is low and does not reflect iron status. During delivery and the postpartum period, hepcidin functions as a marker of inflammation.

Original languageEnglish
JournalThe journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Pages (from-to)1-3
Number of pages3
ISSN1476-7058
DOIs
Publication statusPublished - 29 Jul 2015

ID: 45951761