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Hepatitis C prevalence in Denmark in 2016-An updated estimate using multiple national registers

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Harvard

Nielsen, S, Hansen, JF, Hay, G, Cowan, S, Jepsen, P, Omland, LH, Krarup, HB, Søholm, J, Lazarus, JV, Weis, N, Øvrehus, A & Christensen, PB 2020, 'Hepatitis C prevalence in Denmark in 2016-An updated estimate using multiple national registers' PLoS One, vol. 15, no. 9 September 2020, e0238203, pp. e0238203. https://doi.org/10.1371/journal.pone.0238203

APA

Nielsen, S., Hansen, J. F., Hay, G., Cowan, S., Jepsen, P., Omland, L. H., ... Christensen, P. B. (2020). Hepatitis C prevalence in Denmark in 2016-An updated estimate using multiple national registers. PLoS One, 15(9 September 2020), e0238203. [e0238203]. https://doi.org/10.1371/journal.pone.0238203

CBE

Nielsen S, Hansen JF, Hay G, Cowan S, Jepsen P, Omland LH, Krarup HB, Søholm J, Lazarus JV, Weis N, Øvrehus A, Christensen PB. 2020. Hepatitis C prevalence in Denmark in 2016-An updated estimate using multiple national registers. PLoS One. 15(9 September 2020):e0238203. https://doi.org/10.1371/journal.pone.0238203

MLA

Vancouver

Nielsen S, Hansen JF, Hay G, Cowan S, Jepsen P, Omland LH et al. Hepatitis C prevalence in Denmark in 2016-An updated estimate using multiple national registers. PLoS One. 2020 Sep 1;15(9 September 2020):e0238203. e0238203. https://doi.org/10.1371/journal.pone.0238203

Author

Nielsen, Stine ; Hansen, Janne Fuglsang ; Hay, Gordon ; Cowan, Susan ; Jepsen, Peter ; Omland, Lars Haukali ; Krarup, Henrik Bygum ; Søholm, Jacob ; Lazarus, Jeffrey V ; Weis, Nina ; Øvrehus, Anne ; Christensen, Peer Brehm. / Hepatitis C prevalence in Denmark in 2016-An updated estimate using multiple national registers. In: PLoS One. 2020 ; Vol. 15, No. 9 September 2020. pp. e0238203.

Bibtex

@article{c7f67ff6072244b3b48a72127183018d,
title = "Hepatitis C prevalence in Denmark in 2016-An updated estimate using multiple national registers",
abstract = "BACKGROUND: Chronic hepatitis C (CHC) can be eliminated as a public health threat by meeting the WHO targets: 90{\%} of patients diagnosed and 80{\%} treated by 2030. To achieve and monitor progress towards elimination, an updated estimate of the size of the CHC population is needed, but Denmark has no complete national CHC register. By combining existing registers in 2007, we estimated the population living with CHC to be 16,888 (0.38{\%} of the adult population).AIM: To estimate the population living with diagnosed and undiagnosed CHC in Denmark on 31 December 2016. Among additional aims were to estimate the proportion of patients attending specialised clinical care.METHODS: People with diagnosed CHC were identified from four national registers. The total diagnosed population was estimated by capture-recapture analysis. The undiagnosed population was estimated by comparing the register data with data from two cross-sectional surveys.RESULTS: The population living with diagnosed CHC in Denmark was 7,581 persons (95{\%}CI: 7,416-12,661) of which 6,116 (81{\%}) were identified in the four registers. The estimated undiagnosed fraction was 24{\%}, so the total CHC infected population was 9,975 corresponding to 0.21{\%} of the adult population (95{\%}CI: 9,758-16,659; 0.21{\%}-0.36{\%}). Only 48{\%} of diagnosed patients had received specialised clinical care.CONCLUSION: CHC prevalence in Denmark is declining and 76{\%} of patients have been diagnosed. Linking diagnosed patients to care and increasing efforts to test people with former or current drug use will be necessary to achieve CHC elimination.",
author = "Stine Nielsen and Hansen, {Janne Fuglsang} and Gordon Hay and Susan Cowan and Peter Jepsen and Omland, {Lars Haukali} and Krarup, {Henrik Bygum} and Jacob S{\o}holm and Lazarus, {Jeffrey V} and Nina Weis and Anne {\O}vrehus and Christensen, {Peer Brehm}",
year = "2020",
month = "9",
day = "1",
doi = "10.1371/journal.pone.0238203",
language = "English",
volume = "15",
pages = "e0238203",
journal = "P L o S One",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "9 September 2020",

}

RIS

TY - JOUR

T1 - Hepatitis C prevalence in Denmark in 2016-An updated estimate using multiple national registers

AU - Nielsen, Stine

AU - Hansen, Janne Fuglsang

AU - Hay, Gordon

AU - Cowan, Susan

AU - Jepsen, Peter

AU - Omland, Lars Haukali

AU - Krarup, Henrik Bygum

AU - Søholm, Jacob

AU - Lazarus, Jeffrey V

AU - Weis, Nina

AU - Øvrehus, Anne

AU - Christensen, Peer Brehm

PY - 2020/9/1

Y1 - 2020/9/1

N2 - BACKGROUND: Chronic hepatitis C (CHC) can be eliminated as a public health threat by meeting the WHO targets: 90% of patients diagnosed and 80% treated by 2030. To achieve and monitor progress towards elimination, an updated estimate of the size of the CHC population is needed, but Denmark has no complete national CHC register. By combining existing registers in 2007, we estimated the population living with CHC to be 16,888 (0.38% of the adult population).AIM: To estimate the population living with diagnosed and undiagnosed CHC in Denmark on 31 December 2016. Among additional aims were to estimate the proportion of patients attending specialised clinical care.METHODS: People with diagnosed CHC were identified from four national registers. The total diagnosed population was estimated by capture-recapture analysis. The undiagnosed population was estimated by comparing the register data with data from two cross-sectional surveys.RESULTS: The population living with diagnosed CHC in Denmark was 7,581 persons (95%CI: 7,416-12,661) of which 6,116 (81%) were identified in the four registers. The estimated undiagnosed fraction was 24%, so the total CHC infected population was 9,975 corresponding to 0.21% of the adult population (95%CI: 9,758-16,659; 0.21%-0.36%). Only 48% of diagnosed patients had received specialised clinical care.CONCLUSION: CHC prevalence in Denmark is declining and 76% of patients have been diagnosed. Linking diagnosed patients to care and increasing efforts to test people with former or current drug use will be necessary to achieve CHC elimination.

AB - BACKGROUND: Chronic hepatitis C (CHC) can be eliminated as a public health threat by meeting the WHO targets: 90% of patients diagnosed and 80% treated by 2030. To achieve and monitor progress towards elimination, an updated estimate of the size of the CHC population is needed, but Denmark has no complete national CHC register. By combining existing registers in 2007, we estimated the population living with CHC to be 16,888 (0.38% of the adult population).AIM: To estimate the population living with diagnosed and undiagnosed CHC in Denmark on 31 December 2016. Among additional aims were to estimate the proportion of patients attending specialised clinical care.METHODS: People with diagnosed CHC were identified from four national registers. The total diagnosed population was estimated by capture-recapture analysis. The undiagnosed population was estimated by comparing the register data with data from two cross-sectional surveys.RESULTS: The population living with diagnosed CHC in Denmark was 7,581 persons (95%CI: 7,416-12,661) of which 6,116 (81%) were identified in the four registers. The estimated undiagnosed fraction was 24%, so the total CHC infected population was 9,975 corresponding to 0.21% of the adult population (95%CI: 9,758-16,659; 0.21%-0.36%). Only 48% of diagnosed patients had received specialised clinical care.CONCLUSION: CHC prevalence in Denmark is declining and 76% of patients have been diagnosed. Linking diagnosed patients to care and increasing efforts to test people with former or current drug use will be necessary to achieve CHC elimination.

UR - http://www.scopus.com/inward/record.url?scp=85090319476&partnerID=8YFLogxK

U2 - 10.1371/journal.pone.0238203

DO - 10.1371/journal.pone.0238203

M3 - Journal article

VL - 15

SP - e0238203

JO - P L o S One

JF - P L o S One

SN - 1932-6203

IS - 9 September 2020

M1 - e0238203

ER -

ID: 60791968