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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Heat resistance in extended-spectrum beta-lactamase-producing Escherichia coli may favor environmental survival in a hospital setting

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  1. The membrane transporter PotE is required for virulence in avian pathogenic Escherichia coli (APEC)

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  2. The occurrence of biofilm in an equine experimental wound model of healing by secondary intention

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  3. Typing of Pseudomonas aeruginosa from hemorrhagic pneumonia in mink (Neovison vison)

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  1. Treatment of candidemia in a nationwide setting: increased survival with primary echinocandin treatment

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  2. Update from a twelve-year nationwide fungaemia surveillance: increasing intrinsic and acquired resistance causes concern

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  3. Incidence of HACEK bacteraemia in Denmark: A 6-year population-based study

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  4. High incidence of candidaemia in a nationwide cohort: underlying diseases, risk factors and mortality

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  5. Description and validation of a new automated surveillance system for Clostridium difficile in Denmark

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Nosocomial infections caused by extended-spectrum β-lactamase (ESBL)-producing Escherichia coli are a major concern worldwide. There is an urgent need to identify bacterial factors promoting survival and persistence of these organisms in the nosocomial environment. Here, we describe the presence of a gene cluster, containing the Clp ATPase ClpK, within a collection of Danish ESBL-producing E. coli isolates. The cluster conferred thermoprotection upon the isolates, and thus might facilitate survival on medical devices exposed to semi-high temperatures in a hospital setting.

Original languageEnglish
JournalVeterinary Microbiology
Volume167
Issue number5
Pages (from-to)345-9
Number of pages5
ISSN0378-1135
DOIs
Publication statusPublished - Jun 2016

    Research areas

  • Cross Infection/microbiology, Denmark, Endopeptidase Clp/genetics, Environmental Microbiology, Escherichia coli/enzymology, Hospitals, Hot Temperature, Microbial Viability/radiation effects, Multigene Family, beta-Lactamases/secretion

ID: 55448942