Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Global warming and neurological practice: systematic review

Research output: Contribution to journalReviewResearchpeer-review

DOI

  1. Knee replacement outcome predicted by physiotherapists: a prospective cohort study

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Clinical relevance assessment of animal preclinical research (RAA) tool: development and explanation

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Visual assessment of dynamic knee joint alignment in patients with patellofemoral pain: an agreement study

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Extracellular vesicles in patients in the acute phase of psychosis and after clinical improvement: an explorative study

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Prognostic value of complementary biomarkers of neurodegeneration in a mixed memory clinic cohort

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Questionnaires vs Interviews for the Assessment of Global Functional Outcomes After Traumatic Brain Injury

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Nærdødsoplevelser

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Occurrence and timing of withdrawal of life-sustaining measures in traumatic brain injury patients: a CENTER-TBI study

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

Background: Climate change, including global warming, will cause poorer global health and rising numbers of environmental refugees. As neurological disorders account for a major share of morbidity and mortality worldwide, global warming is also destined to alter neurological practice; however, to what extent and by which mechanisms is unknown. We aimed to collect information about the effects of ambient temperatures and human migration on the epidemiology and clinical manifestations of neurological disorders.

Methods: We searched PubMed and Scopus from 01/2000 to 12/2020 for human studies addressing the influence of ambient temperatures and human migration on Alzheimer's and non-Alzheimer's dementia, epilepsy, headache/migraine, multiple sclerosis, Parkinson's disease, stroke, and tick-borne encephalitis (a model disease for neuroinfections). The protocol was pre-registered with PROSPERO (2020 CRD42020147543).

Results: Ninety-three studies met inclusion criteria, 84 of which reported on ambient temperatures and nine on migration. Overall, most temperature studies suggested a relationship between increasing temperatures and higher mortality and/or morbidity, whereas results were more ambiguous for migration studies. However, we were unable to identify a single adequately designed study addressing how global warming and human migration will change neurological practice. Still, extracted data indicated multiple ways by which these aspects might alter neurological morbidity and mortality soon.

Conclusion: Significant heterogeneity exists across studies with respect to methodology, outcome measures, confounders and study design, including lack of data from low-income countries, but the evidence so far suggests that climate change will affect the practice of all major neurological disorders in the near future. Adequately designed studies to address this issue are urgently needed, requiring concerted efforts from the entire neurological community.

Original languageEnglish
Article numbere11941
JournalPeerJ
Volume9
Pages (from-to)e11941
ISSN2167-8359
DOIs
Publication statusPublished - 4 Aug 2021

    Research areas

  • Alzheimer dementia, Climate change, Epidemiology, Epilepsy, Global warming, Migraine, Migration, Multiple sclerosis, Neurology, Stroke

ID: 67641884