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Genterapi til sygdomme i centralnervesystemet

Research output: Contribution to journalJournal articlepeer-review

  1. Screening, diagnostik og behandling af cervixcancer i graviditeten

    Research output: Contribution to journalJournal articlepeer-review

  2. Hybridbehandling af proteintabende enteropati hos patient med univentrikulærtkredsløb

    Research output: Contribution to journalJournal articlepeer-review

  3. Avanceret lokoregionalt thoraxvægsrecidiv af brystkræft

    Research output: Contribution to journalReviewpeer-review

  4. Konservativ behandling af iatrogen mælkefistel

    Research output: Contribution to journalJournal articlepeer-review

  5. Abdominalmuskelparese som en sjælden præsentation af neuroborreliose

    Research output: Contribution to journalJournal articlepeer-review

  1. Automated ictal EEG source imaging: A retrospective, blinded clinical validation study

    Research output: Contribution to journalJournal articlepeer-review

  2. An fMRI-compatible system for targeted electrical stimulation

    Research output: Contribution to journalJournal articlepeer-review

  3. Depression og angst hos voksne patienter med epilepsi

    Research output: Contribution to journalReviewpeer-review

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In recent years, gene therapy has resurged as a potential treatment for an increasing number of medical diseases including those affecting the central nervous system (CNS), which is discussed in this review. Clinical trials have revealed promising results particularly in gene therapy for Parkinson's disease with upregulation of dopamine synthesis or downregulation of huntingtin synthesis in Huntington's disease. Gene therapy for spinal motor atrophy has received FDA approval this year. The biggest success is seen in ophthalmology, where gene therapy has been FDA/EU-approved for retinitis pigmentosa, sparking further hope of use for other CNS diseases in a near future.

Translated title of the contributionGene therapy for central nervous system disorders
Original languageDanish
JournalUgeskrift for Laeger
Volume182
Issue number3
Pages (from-to)V09190535
ISSN0041-5782
Publication statusPublished - 13 Jan 2020

ID: 61290371