Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Genomic medicine as consumer goods

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Allergisk kontakteksem ved anvendelse af insulinpumper og glukosesensorer hos børn med diabetes

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Remdesivir til behandling af COVID-19-pneumoni

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Stilheden før stormen - om psykiatrisk sygdom i coronaens tid

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Varicocele Testis

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Integration af specialiseret palliation og onkologi

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Association between Mental Disorders and Subsequent Medical Conditions

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Autism spectrum disorder and attention deficit hyperactivity disorder have a similar burden of rare protein-truncating variants

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

In this review, current trends in personal genetics are covered. The main differences between the "classic" rare high-effect mutations vs the combined effects of thousands of common, low-risk variants are outlined, and then we provide examples of possible clinical use of microarray-based genetic measurements of rare high-risk mutations, and diagnosis-specific polygenic risk scores. The aim of this review is to discuss the possible clinical relevance vs the hyped and potentially harmful overinterpretations of direct-to-consumer genetics services.

Original languageEnglish
JournalUgeskrift for Laeger
Volume181
Issue number7A
ISSN0041-5782
Publication statusPublished - 1 Apr 2019

ID: 58594780