Genome-wide association study of multiplex schizophrenia pedigrees

Douglas F Levinson; Jianxin Shi; Kai Wang; Sang Oh; Brien Riley; Ann E Pulver; Dieter B Wildenauer; Claudine Laurent; Bryan J Mowry; Pablo V Gejman; Michael J Owen; Kenneth S Kendler; Gerald Nestadt; Sibylle G Schwab; Jacques Mallet; Deborah Nertney; Alan R Sanders; Nigel M Williams; Brandon Wormley; Virginia K Lasseter; Margot Albus; Stephanie Godard-Bauché; Madeline Alexander; Jubao Duan; Michael C O'Donovan; Dermot Walsh; Anthony O'Neill; George N Papadimitriou; Dimitris Dikeos; Wolfgang Maier; Bernard Lerer; Dominique Campion; David Cohen; Maurice Jay; Ayman Fanous; Peter Eichhammer; Jeremy M Silverman; Nadine Norton; Nancy Zhang; Hakon Hakonarson; Cynthia Gao; Ami Citri; Mark Hansen; Stephan Ripke; Frank Dudbridge; Peter A Holmans; Schizophrenia Psychiatric GWAS Consortium

doi:10.1176/appi.ajp.2012.11091423

Genome-wide association study of multiplex schizophrenia pedigrees

Douglas F Levinson, Jianxin Shi, Kai Wang, Sang Oh, Brien Riley, Ann E Pulver, Dieter B Wildenauer, Claudine Laurent, Bryan J Mowry, Pablo V Gejman, Michael J Owen, Kenneth S Kendler, Gerald Nestadt, Sibylle G Schwab, Jacques Mallet, Deborah Nertney, Alan R Sanders, Nigel M Williams, Brandon Wormley, Virginia K LasseterMargot Albus, Stephanie Godard-Bauché, Madeline Alexander, Jubao Duan, Michael C O'Donovan, Dermot Walsh, Anthony O'Neill, George N Papadimitriou, Dimitris Dikeos, Wolfgang Maier, Bernard Lerer, Dominique Campion, David Cohen, Maurice Jay, Ayman Fanous, Peter Eichhammer, Jeremy M Silverman, Nadine Norton, Nancy Zhang, Hakon Hakonarson, Cynthia Gao, Ami Citri, Mark Hansen, Stephan Ripke, Frank Dudbridge, Peter A Holmans, Schizophrenia Psychiatric GWAS Consortium

56 Citations (Scopus)

Abstract

The authors used a genome-wide association study (GWAS) of multiply affected families to investigate the association of schizophrenia to common single-nucleotide polymorphisms (SNPs) and rare copy number variants (CNVs).

Original language	English
Journal	The American journal of psychiatry
Volume	169
Issue number	9
Pages (from-to)	963-73
Number of pages	11
DOIs	https://doi.org/10.1176/appi.ajp.2012.11091423
Publication status	Published - Sept 2012

Keywords

African Continental Ancestry Group
Case-Control Studies
DNA Copy Number Variations
European Continental Ancestry Group
Female
Genetic Predisposition to Disease
Genome-Wide Association Study
Genotype
Humans
Male
Pedigree
Polymorphism, Single Nucleotide
Schizophrenia

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Levinson, D. F., Shi, J., Wang, K., Oh, S., Riley, B., Pulver, A. E., Wildenauer, D. B., Laurent, C., Mowry, B. J., Gejman, P. V., Owen, M. J., Kendler, K. S., Nestadt, G., Schwab, S. G., Mallet, J., Nertney, D., Sanders, A. R., Williams, N. M., Wormley, B., ... Schizophrenia Psychiatric GWAS Consortium (2012). Genome-wide association study of multiplex schizophrenia pedigrees. The American journal of psychiatry, 169(9), 963-73. https://doi.org/10.1176/appi.ajp.2012.11091423

Levinson, DF, Shi, J, Wang, K, Oh, S, Riley, B, Pulver, AE, Wildenauer, DB, Laurent, C, Mowry, BJ, Gejman, PV, Owen, MJ, Kendler, KS, Nestadt, G, Schwab, SG, Mallet, J, Nertney, D, Sanders, AR, Williams, NM, Wormley, B, Lasseter, VK, Albus, M, Godard-Bauché, S, Alexander, M, Duan, J, O'Donovan, MC, Walsh, D, O'Neill, A, Papadimitriou, GN, Dikeos, D, Maier, W, Lerer, B, Campion, D, Cohen, D, Jay, M, Fanous, A, Eichhammer, P, Silverman, JM, Norton, N, Zhang, N, Hakonarson, H, Gao, C, Citri, A, Hansen, M, Ripke, S, Dudbridge, F, Holmans, PA & Schizophrenia Psychiatric GWAS Consortium 2012, 'Genome-wide association study of multiplex schizophrenia pedigrees', The American journal of psychiatry, vol. 169, no. 9, pp. 963-73. https://doi.org/10.1176/appi.ajp.2012.11091423

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AU - Mallet, Jacques

AU - Nertney, Deborah

AU - Sanders, Alan R

AU - Williams, Nigel M

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AU - Albus, Margot

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AU - Alexander, Madeline

AU - Duan, Jubao

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AU - Walsh, Dermot

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AU - Eichhammer, Peter

AU - Silverman, Jeremy M

AU - Norton, Nadine

AU - Zhang, Nancy

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AU - Citri, Ami

AU - Hansen, Mark

AU - Ripke, Stephan

AU - Dudbridge, Frank

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KW - DNA Copy Number Variations

KW - European Continental Ancestry Group

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KW - Genetic Predisposition to Disease

KW - Genome-Wide Association Study

KW - Genotype

KW - Humans

KW - Male

KW - Pedigree

KW - Polymorphism, Single Nucleotide

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SP - 963

EP - 973

JO - The American journal of psychiatry

JF - The American journal of psychiatry

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ER -

Genome-wide association study of multiplex schizophrenia pedigrees

Abstract

Keywords

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