Abstract
The aim of the present review was to present clinical aspects of recent research in genes, the experience of stressful life events and depression. 60-70% experience a moderate to severe stressful life event half a year prior to the first onset of depression, whereas later depressive episodes to a lesser extent are preceded by stressful life events. Clinical features do not differ between depressions with or without prior stressful life events. Certain genetic variations in the serotonin receptor system seem to increase the risk of developing depression in relation to experiencing stressful life events.
| Translated title of the contribution | Genetics and stressful life events interact in depression |
|---|---|
| Original language | Danish |
| Journal | Ugeskrift for Laeger |
| Volume | 175 |
| Issue number | 14 |
| Pages (from-to) | 948-51 |
| Number of pages | 4 |
| ISSN | 0041-5782 |
| Publication status | Published - 1 Apr 2013 |