Genetic variation in ABCA1 predicts ischemic heart disease in the general population

Ruth Frikke-Schmidt; Børge G Nordestgaard; Gorm B Jensen; Rolf Steffensen; Anne Tybjaerg-Hansen

doi:10.1161/ATVBAHA.107.153858

Genetic variation in ABCA1 predicts ischemic heart disease in the general population

Ruth Frikke-Schmidt, Børge G Nordestgaard, Gorm B Jensen, Rolf Steffensen, Anne Tybjaerg-Hansen

125 Citations (Scopus)

Abstract

We tested the hypothesis that 6 nonsynonymous single nucleotide polymorphisms (SNPs) in ATP-Binding-Cassette transporter A1 (ABCA1) affect risk of ischemic heart disease (IHD) in the general population.

Original language	English
Journal	Arteriosclerosis, Thrombosis, and Vascular Biology
Volume	28
Issue number	1
Pages (from-to)	180-6
Number of pages	7
ISSN	1079-5642
DOIs	https://doi.org/10.1161/ATVBAHA.107.153858
Publication status	Published - 2008

Keywords

ATP-Binding Cassette Transporters
Adult
Case-Control Studies
Denmark
Female
Follow-Up Studies
Genetic Predisposition to Disease
Humans
Linkage Disequilibrium
Male
Middle Aged
Myocardial Ischemia
Odds Ratio
Polymorphism, Single Nucleotide

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10.1161/ATVBAHA.107.153858

http://atvb.ahajournals.org/cgi/content/full/28/1/180

Cite this

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abstract = "We tested the hypothesis that 6 nonsynonymous single nucleotide polymorphisms (SNPs) in ATP-Binding-Cassette transporter A1 (ABCA1) affect risk of ischemic heart disease (IHD) in the general population.",

keywords = "ATP-Binding Cassette Transporters, Adult, Case-Control Studies, Denmark, Female, Follow-Up Studies, Genetic Predisposition to Disease, Humans, Linkage Disequilibrium, Male, Middle Aged, Myocardial Ischemia, Odds Ratio, Polymorphism, Single Nucleotide",

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AU - Nordestgaard, Børge G

AU - Jensen, Gorm B

AU - Steffensen, Rolf

AU - Tybjaerg-Hansen, Anne

PY - 2008

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KW - Case-Control Studies

KW - Denmark

KW - Female

KW - Follow-Up Studies

KW - Genetic Predisposition to Disease

KW - Humans

KW - Linkage Disequilibrium

KW - Male

KW - Middle Aged

KW - Myocardial Ischemia

KW - Odds Ratio

KW - Polymorphism, Single Nucleotide

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Genetic variation in ABCA1 predicts ischemic heart disease in the general population

Abstract

Keywords

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