Genetic modifier of the QTc interval associated with early-onset atrial fibrillation

Laura Andreasen, Jonas B Nielsen, Ingrid E Christophersen, Anders Gaarsdal Holst, Ahmad Sajadieh, Arnljot Tveit, Stig Haunsø, Jesper H Svendsen, Nicole Schmitt, Morten S Olesen

9 Citations (Scopus)

Abstract

Both shortening and prolongation of the QTc interval have been associated with atrial fibrillation (AF). We investigated whether 8 single nucleotide polymorphisms (SNPs) at loci previously shown to affect QTc interval duration were associated with lone AF.
Original languageEnglish
JournalThe Canadian journal of cardiology
Volume29
Issue number10
Pages (from-to)1234-40
Number of pages7
ISSN0828-282X
DOIs
Publication statusPublished - Oct 2013

Keywords

  • Adolescent
  • Adult
  • Age of Onset
  • Atrial Fibrillation
  • Confidence Intervals
  • DNA
  • DNA Mutational Analysis
  • Denmark
  • Electrocardiography
  • Ether-A-Go-Go Potassium Channels
  • Female
  • Follow-Up Studies
  • Gene Frequency
  • Genetic Predisposition to Disease
  • Genotype
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Mutation
  • Odds Ratio
  • Young Adult

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