Genetic determinants of LDL, lipoprotein(a), triglyceride-rich lipoproteins and HDL: concordance and discordance with cardiovascular disease risk

53 Citations (Scopus)

Abstract

To evaluate whether new and known genetic determinants of plasma levels of LDL cholesterol, lipoprotein(a), triglyceride-rich lipoproteins, and HDL cholesterol associate with the risk of cardiovascular disease expected from the effect on lipoprotein levels. Concordance or discordance of such genetic determinants with cardiovascular disease risk will either favor or disfavor that these lipoproteins are causally related to cardiovascular disease.
Original languageEnglish
JournalCurrent Opinion in Lipidology
Volume22
Issue number2
Pages (from-to)113-22
Number of pages10
ISSN0957-9672
DOIs
Publication statusPublished - 2011

Keywords

  • Cardiovascular Diseases
  • Cholesterol, HDL
  • Humans
  • Lipoprotein(a)
  • Lipoproteins
  • Risk Factors

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