Gastrin in pituitary tumours

L Bardram; J Lindholm; J F Rehfeld

doi:10.1530/acta.0.1150419

Gastrin in pituitary tumours

L Bardram, J Lindholm, J F Rehfeld

12 Citations (Scopus)

Abstract

Twelve of 87 pituitary adenomas from patients with acromegaly, Cushing's syndrome. Nelson's syndrome, hyperprolactinaemia and without symptoms of hormone hypersecretion contained gastrin in concentrations from 0.5 to 166 pmol/g. Only ACTH-producing tumours contained gastrin, which occurred in forms smaller than those present in the normal adenohypophysis. The results indicate that corticotropic tumours may synthesize gastrin in moderate amounts.

Original language	English
Journal	Acta Endocrinologica
Volume	115
Issue number	3
Pages (from-to)	419-22
Number of pages	4
ISSN	0001-5598
DOIs	https://doi.org/10.1530/acta.0.1150419
Publication status	Published - Jul 1987
Externally published	Yes

Keywords

Adenoma/analysis
Chromatography, Gel
Gastrins/analysis
Humans
Molecular Conformation
Pituitary Gland, Anterior/analysis
Pituitary Neoplasms/analysis
Radioimmunoassay

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10.1530/acta.0.1150419

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title = "Gastrin in pituitary tumours",

abstract = "Twelve of 87 pituitary adenomas from patients with acromegaly, Cushing's syndrome. Nelson's syndrome, hyperprolactinaemia and without symptoms of hormone hypersecretion contained gastrin in concentrations from 0.5 to 166 pmol/g. Only ACTH-producing tumours contained gastrin, which occurred in forms smaller than those present in the normal adenohypophysis. The results indicate that corticotropic tumours may synthesize gastrin in moderate amounts.",

keywords = "Adenoma/analysis, Chromatography, Gel, Gastrins/analysis, Humans, Molecular Conformation, Pituitary Gland, Anterior/analysis, Pituitary Neoplasms/analysis, Radioimmunoassay",

author = "L Bardram and J Lindholm and Rehfeld, \{J F\}",

year = "1987",

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language = "English",

volume = "115",

pages = "419--22",

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TY - JOUR

T1 - Gastrin in pituitary tumours

AU - Bardram, L

AU - Lindholm, J

AU - Rehfeld, J F

PY - 1987/7

Y1 - 1987/7

N2 - Twelve of 87 pituitary adenomas from patients with acromegaly, Cushing's syndrome. Nelson's syndrome, hyperprolactinaemia and without symptoms of hormone hypersecretion contained gastrin in concentrations from 0.5 to 166 pmol/g. Only ACTH-producing tumours contained gastrin, which occurred in forms smaller than those present in the normal adenohypophysis. The results indicate that corticotropic tumours may synthesize gastrin in moderate amounts.

AB - Twelve of 87 pituitary adenomas from patients with acromegaly, Cushing's syndrome. Nelson's syndrome, hyperprolactinaemia and without symptoms of hormone hypersecretion contained gastrin in concentrations from 0.5 to 166 pmol/g. Only ACTH-producing tumours contained gastrin, which occurred in forms smaller than those present in the normal adenohypophysis. The results indicate that corticotropic tumours may synthesize gastrin in moderate amounts.

KW - Adenoma/analysis

KW - Chromatography, Gel

KW - Gastrins/analysis

KW - Humans

KW - Molecular Conformation

KW - Pituitary Gland, Anterior/analysis

KW - Pituitary Neoplasms/analysis

KW - Radioimmunoassay

UR - https://www.scopus.com/pages/publications/0023177792

U2 - 10.1530/acta.0.1150419

DO - 10.1530/acta.0.1150419

M3 - Journal article

C2 - 3618087

SN - 0001-5598

VL - 115

SP - 419

EP - 422

JO - Acta Endocrinologica

JF - Acta Endocrinologica

IS - 3

ER -

Gastrin in pituitary tumours

Abstract

Keywords

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