Abstract
Galactose elimination kinetics was studied in isolated perfused livers (single pass) from rats subjected to two thirds partial hepatectomy 6 h earlier or immediately before investigation. No difference was found between the two groups in the maximum galactose elimination rate or in the half saturation galactose concentration. This is in contrast with in vivo observation of restored galactose elimination capacity 6 h after two thirds hepatectomy. The discrepancy indicates that extrahepatic factors may be of importance for the metabolic regulation in the liver during regeneration.
Original language | English |
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Journal | Scandinavian Journal of Clinical and Laboratory Investigation |
Volume | 44 |
Issue number | 2 |
Pages (from-to) | 155-8 |
Number of pages | 4 |
ISSN | 0036-5513 |
DOIs | |
Publication status | Published - Apr 1984 |
Keywords
- Animals
- Female
- Galactose/metabolism
- Hepatectomy
- Kinetics
- Liver/metabolism
- Liver Regeneration
- Perfusion
- Rats
- Rats, Inbred Strains