Galactose elimination kinetics in perfused rat liver after two thirds hepatectomy

H E Poulsen, H Vilstrup, S Keiding

4 Citations (Scopus)

Abstract

Galactose elimination kinetics was studied in isolated perfused livers (single pass) from rats subjected to two thirds partial hepatectomy 6 h earlier or immediately before investigation. No difference was found between the two groups in the maximum galactose elimination rate or in the half saturation galactose concentration. This is in contrast with in vivo observation of restored galactose elimination capacity 6 h after two thirds hepatectomy. The discrepancy indicates that extrahepatic factors may be of importance for the metabolic regulation in the liver during regeneration.

Original languageEnglish
JournalScandinavian Journal of Clinical and Laboratory Investigation
Volume44
Issue number2
Pages (from-to)155-8
Number of pages4
ISSN0036-5513
DOIs
Publication statusPublished - Apr 1984

Keywords

  • Animals
  • Female
  • Galactose/metabolism
  • Hepatectomy
  • Kinetics
  • Liver/metabolism
  • Liver Regeneration
  • Perfusion
  • Rats
  • Rats, Inbred Strains

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