Further studies on Hb Canebière [β12(G4)Asn→His], a low affinity hemoglobin variant

Ulf Froelund; Erik Sandbakken; Pal Bela Szecsi; Henrik Birgens

doi:10.3109/03630269.2010.511593

Further studies on Hb Canebière [β12(G4)Asn→His], a low affinity hemoglobin variant

Ulf Froelund, Erik Sandbakken, Pal Bela Szecsi, Henrik Birgens

2 Citations (Scopus)

Abstract

A case of Hb Canebière [β102(G4)Asn→His] was diagnosed in an otherwise healthy 21-year-old Danish woman. The clinical consequences were minor, since her only symptom consisted of transient cyanosis in lips and fingers when exposed to cold environments. Whole blood p50 was 59.9 mmHg. The Hb Canebière variant could not be separated from Hb A by high performance liquid chromatography (HPLC) and isoelectric focusing (IEF), and it was thus missed by routine hemoglobin (Hb) fractionation techniques.

Original language	English
Journal	Hemoglobin
Volume	34
Issue number	5
Pages (from-to)	495-9
Number of pages	5
ISSN	0363-0269
DOIs	https://doi.org/10.3109/03630269.2010.511593
Publication status	Published - 1 Jan 2010

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10.3109/03630269.2010.511593

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title = "Further studies on Hb Canebi{\`e}re [β12(G4)Asn→His], a low affinity hemoglobin variant",

abstract = "A case of Hb Canebi{\`e}re [β102(G4)Asn→His] was diagnosed in an otherwise healthy 21-year-old Danish woman. The clinical consequences were minor, since her only symptom consisted of transient cyanosis in lips and fingers when exposed to cold environments. Whole blood p50 was 59.9 mmHg. The Hb Canebi{\`e}re variant could not be separated from Hb A by high performance liquid chromatography (HPLC) and isoelectric focusing (IEF), and it was thus missed by routine hemoglobin (Hb) fractionation techniques.",

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T1 - Further studies on Hb Canebière [β12(G4)Asn→His], a low affinity hemoglobin variant

AU - Froelund, Ulf

AU - Sandbakken, Erik

AU - Szecsi, Pal Bela

AU - Birgens, Henrik

PY - 2010/1/1

Y1 - 2010/1/1

N2 - A case of Hb Canebière [β102(G4)Asn→His] was diagnosed in an otherwise healthy 21-year-old Danish woman. The clinical consequences were minor, since her only symptom consisted of transient cyanosis in lips and fingers when exposed to cold environments. Whole blood p50 was 59.9 mmHg. The Hb Canebière variant could not be separated from Hb A by high performance liquid chromatography (HPLC) and isoelectric focusing (IEF), and it was thus missed by routine hemoglobin (Hb) fractionation techniques.

AB - A case of Hb Canebière [β102(G4)Asn→His] was diagnosed in an otherwise healthy 21-year-old Danish woman. The clinical consequences were minor, since her only symptom consisted of transient cyanosis in lips and fingers when exposed to cold environments. Whole blood p50 was 59.9 mmHg. The Hb Canebière variant could not be separated from Hb A by high performance liquid chromatography (HPLC) and isoelectric focusing (IEF), and it was thus missed by routine hemoglobin (Hb) fractionation techniques.

UR - https://www.scopus.com/pages/publications/77956918993

U2 - 10.3109/03630269.2010.511593

DO - 10.3109/03630269.2010.511593

M3 - Journal article

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SP - 495

EP - 499

JO - Hemoglobin

JF - Hemoglobin

IS - 5

ER -

Further studies on Hb Canebière [β12(G4)Asn→His], a low affinity hemoglobin variant

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