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The Capital Region of Denmark - a part of Copenhagen University Hospital
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FSHB-211 and FSHR 2039 are associated with serum levels of follicle-stimulating hormone and antimüllerian hormone in healthy girls: a longitudinal cohort study

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  1. Psychological stress, stressful life events, male factor infertility, and testicular function: a cross-sectional study

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  2. Therapeutic endometrial scratching and implantation after in vitro fertilization: a multicenter randomized controlled trial

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  3. Associations of different molecular forms of antimüllerian hormone and biomarkers of polycystic ovary syndrome and normal women

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  1. Evaluation of Serum Insulin-like Factor 3 Quantification by LC-MS/MS as a Biomarker of Leydig Cell Function

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  2. Use of stored serum in the study of time trends and geographical differences in exposure of pregnant women to phthalates

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  3. Increases in bioactive IGF do not parallel increases in total IGF-I during growth hormone treatment of children born SGA

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To investigate whether genetic polymorphisms in the FSH pathway (FSHB-211 G→T and FSHR 2039 A→G) affect serum levels of FSH, antimüllerian hormone (AMH), and age at pubertal onset. FSH secretion and FSH signal transduction are enhanced in carriers of FSHB GG and FSHR AA, respectively. Furthermore, the combined genotype FSHB GG+FSHR AA is the most favorable for male gonadal function, but the effect of this genotype has never been evaluated in peripubertal females. AMH is a marker of ovarian function and is negatively correlated with FSH in prepubertal girls.
Original languageEnglish
JournalFertility and Sterility
Volume100
Issue number4
Pages (from-to)1089-1095
ISSN0015-0282
DOIs
Publication statusPublished - 11 Jul 2013

ID: 39023528