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Fructans of Jerusalem artichokes: intestinal transport, absorption, fermentation, and influence on blood glucose, insulin, and C-peptide responses in healthy subjects

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  1. Intestinal sensing and handling of dietary lipids in gastric bypass-operated patients and matched controls

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  2. Abdominal adiposity and cardiometabolic risk factors in children and adolescents: a Mendelian randomization analysis

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  3. Body mass index trajectories in early childhood in relation to cardiometabolic risk profile and body composition at 5 years of age

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  4. A prospective study of artificially sweetened beverage intake and cardiometabolic health among women at high risk

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  1. The association of celiac disease and allergic disease in a general adult population

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  2. Medicinsk Kompendium: Tarmsygdomme

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  3. A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults

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  4. The distribution of HLA DQ2 and DQ8 haplotypes and their association with health indicators in a general Danish population

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Fructans are naturally occurring plant oligosaccharides with sweetening properties. Fructans (FAs) isolated from Jerusalem artichokes (Helianthus tuberosus) were studied with respect to intestinal handling and influence on blood glucose (BG), insulin, and C-peptide responses in eight healthy subjects. The responses were compared with those for fructose ingestion. The effect of FAs added to a wheat-starch meal was also studied. Standardized breath-hydrogen excretion indicated that FAs were completely malabsorbed and, after a 20-g dose, traces of FA were detected in 24-h urine collections in one subject only. Orocecal transit times were longer for FAs than for lactulose and fructose. The BG and insulin increments were very low after FA ingestion, lower than after fructose ingestion, whereas hydrogen production was much higher. Areas under BG curves tended to be smaller when 10 g FA was added to a 50-g wheat-starch meal, but there was no apparent interference with starch absorption.
Original languageEnglish
JournalThe American journal of clinical nutrition
Volume52
Issue number4
Pages (from-to)675-81
Number of pages7
ISSN0002-9165
Publication statusPublished - Oct 1990

    Research areas

  • Absorption, Adult, Biological Transport, Blood Glucose, C-Peptide, Female, Fermentation, Fructans, Gastrointestinal Transit, Helianthus, Humans, Hydrogen, Insulin, Intestines, Male, Polysaccharides, Starch, Time Factors, Triticum

ID: 39697186