Frequency and impact of obstetric complications prior and subsequent to unexplained secondary recurrent miscarriage

Henriette Svarre Nielsen, Rudi Nora Steffensen, Marie Lund, Lisbeth Egestad, Laust Hvas Mortensen, Anne-Marie Nybo Andersen, Ø Lidegaard, O B Christiansen

51 Citations (Scopus)

Abstract

The chance of a live birth after a diagnosis of secondary recurrent miscarriage (SRM) is reduced in patients who, prior to the miscarriages, gave birth to a boy and carry HLA class II alleles that efficiently present male-specific (H-Y) antigens to the immune system. Information about obstetric complications in births prior and subsequent to the SRM diagnosis is limited. The relations between maternal carriage of H-Y-restricting HLA, fetal sex, obstetric complications and prognosis are unknown.
Original languageEnglish
JournalHuman Reproduction
Volume25
Issue number6
Pages (from-to)1543-52
Number of pages10
ISSN0268-1161
DOIs
Publication statusPublished - 1 Jun 2010

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