Four days of muscle disuse impairs single fiber contractile function in young and old healthy men

Lars G Hvid; Charlotte Suetta; Per Aagaard; Michael Kjaer; Ulrik Frandsen; Niels Ortenblad

doi:10.1016/j.exger.2012.11.005

Four days of muscle disuse impairs single fiber contractile function in young and old healthy men

Lars G Hvid
, Charlotte Suetta
, Per Aagaard
, Michael Kjaer
, Ulrik Frandsen
, Niels Ortenblad

61 Citations (Scopus)

Abstract

The purpose of the study was to investigate the effects of 4days of disuse (knee brace) on contractile function of isolated vastus lateralis fibers (n=486) from 11 young (24.3±0.9yrs) and 11 old (67.2±1.0yrs) healthy men having comparable levels of physical activity. Prior to disuse single fiber specific force (maximal Ca(2+)-activated force per cross-sectional area) was lower in MHC I vs. IIa fibers (p

Original language	English
Journal	Experimental Gerontology
Volume	48
Issue number	2
Pages (from-to)	154-61
Number of pages	8
ISSN	0531-5565
DOIs	https://doi.org/10.1016/j.exger.2012.11.005
Publication status	Published - 2013

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10.1016/j.exger.2012.11.005

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abstract = "The purpose of the study was to investigate the effects of 4days of disuse (knee brace) on contractile function of isolated vastus lateralis fibers (n=486) from 11 young (24.3±0.9yrs) and 11 old (67.2±1.0yrs) healthy men having comparable levels of physical activity. Prior to disuse single fiber specific force (maximal Ca(2+)-activated force per cross-sectional area) was lower in MHC I vs. IIa fibers (p",

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AU - Hvid, Lars G

AU - Suetta, Charlotte

AU - Aagaard, Per

AU - Kjaer, Michael

AU - Frandsen, Ulrik

AU - Ortenblad, Niels

PY - 2013

Y1 - 2013

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AB - The purpose of the study was to investigate the effects of 4days of disuse (knee brace) on contractile function of isolated vastus lateralis fibers (n=486) from 11 young (24.3±0.9yrs) and 11 old (67.2±1.0yrs) healthy men having comparable levels of physical activity. Prior to disuse single fiber specific force (maximal Ca(2+)-activated force per cross-sectional area) was lower in MHC I vs. IIa fibers (p

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DO - 10.1016/j.exger.2012.11.005

M3 - Journal article

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Four days of muscle disuse impairs single fiber contractile function in young and old healthy men

Abstract

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