Forhøjet intrakranielt tryk ved akut bakteriel meningitis

Christine Lodberg Hvas; Åse Bengård Andersen; Kirsten Møller; Klaus Hansen; Frantz Rom Poulsen; Christian Overgaard-Steensen

Forhøjet intrakranielt tryk ved akut bakteriel meningitis

Translated title of the contribution: Increased intracranial pressure in acute bacterial meningitis

Christine Lodberg Hvas
, Åse Bengård Andersen
, Kirsten Møller
, Klaus Hansen
, Frantz Rom Poulsen
, Christian Overgaard-Steensen

Abstract

Acute bacterial meningitis (ABM) is associated with increased intracranial pressure (ICP) caused by bacterial invasion and the host response to infection. Antibiotic therapy is a sine qua non, and adjunct dexamethasone decreases mortality. The ICP increase may have a rapid course and death due to herniation is most often seen within the first week. Evidence regarding treatment of increased ICP in ABM is limited; this review summarises observational studies which point towards reduced mortality by applying a structured approach towards normalization of ICP in ABM.

Translated title of the contribution	Increased intracranial pressure in acute bacterial meningitis
Original language	Danish
Article number	V06230363
Journal	Ugeskrift for Laeger
Volume	185
Issue number	51
ISSN	0041-5782
Publication status	Published - 18 Dec 2023

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https://ugeskriftet.dk/videnskab/forhojet-intrakranielt-tryk-ved-akut-bakteriel-meningitis

Cite this

@article{89c7cff6e3bd49c8a2f18300cf5ba766,

title = "Forh{\o}jet intrakranielt tryk ved akut bakteriel meningitis",

abstract = "Acute bacterial meningitis (ABM) is associated with increased intracranial pressure (ICP) caused by bacterial invasion and the host response to infection. Antibiotic therapy is a sine qua non, and adjunct dexamethasone decreases mortality. The ICP increase may have a rapid course and death due to herniation is most often seen within the first week. Evidence regarding treatment of increased ICP in ABM is limited; this review summarises observational studies which point towards reduced mortality by applying a structured approach towards normalization of ICP in ABM.",

keywords = "Anti-Bacterial Agents/therapeutic use, Humans, Intracranial Hypertension/drug therapy, Intracranial Pressure, Meningitis, Bacterial/drug therapy",

author = "Hvas, \{Christine Lodberg\} and Andersen, \{{\AA}se Beng{\aa}rd\} and Kirsten M{\o}ller and Klaus Hansen and Poulsen, \{Frantz Rom\} and Christian Overgaard-Steensen",

note = "Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.",

year = "2023",

month = dec,

day = "18",

language = "Dansk",

volume = "185",

journal = "Ugeskrift for Laeger",

issn = "0041-5782",

publisher = "Almindelige Danske L{\ae}geforening",

number = "51",

}

TY - JOUR

T1 - Forhøjet intrakranielt tryk ved akut bakteriel meningitis

AU - Hvas, Christine Lodberg

AU - Andersen, Åse Bengård

AU - Møller, Kirsten

AU - Hansen, Klaus

AU - Poulsen, Frantz Rom

AU - Overgaard-Steensen, Christian

N1 - Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.

PY - 2023/12/18

Y1 - 2023/12/18

N2 - Acute bacterial meningitis (ABM) is associated with increased intracranial pressure (ICP) caused by bacterial invasion and the host response to infection. Antibiotic therapy is a sine qua non, and adjunct dexamethasone decreases mortality. The ICP increase may have a rapid course and death due to herniation is most often seen within the first week. Evidence regarding treatment of increased ICP in ABM is limited; this review summarises observational studies which point towards reduced mortality by applying a structured approach towards normalization of ICP in ABM.

AB - Acute bacterial meningitis (ABM) is associated with increased intracranial pressure (ICP) caused by bacterial invasion and the host response to infection. Antibiotic therapy is a sine qua non, and adjunct dexamethasone decreases mortality. The ICP increase may have a rapid course and death due to herniation is most often seen within the first week. Evidence regarding treatment of increased ICP in ABM is limited; this review summarises observational studies which point towards reduced mortality by applying a structured approach towards normalization of ICP in ABM.

KW - Anti-Bacterial Agents/therapeutic use

KW - Humans

KW - Intracranial Hypertension/drug therapy

KW - Intracranial Pressure

KW - Meningitis, Bacterial/drug therapy

UR - https://www.scopus.com/pages/publications/85180276385

M3 - Review

C2 - 38105735

SN - 0041-5782

VL - 185

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 51

M1 - V06230363

ER -

Forhøjet intrakranielt tryk ved akut bakteriel meningitis

Abstract

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