TY - JOUR
T1 - Forhøjet intrakranielt tryk ved akut bakteriel meningitis
AU - Hvas, Christine Lodberg
AU - Andersen, Åse Bengård
AU - Møller, Kirsten
AU - Hansen, Klaus
AU - Poulsen, Frantz Rom
AU - Overgaard-Steensen, Christian
N1 - Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.
PY - 2023/12/18
Y1 - 2023/12/18
N2 - Acute bacterial meningitis (ABM) is associated with increased intracranial pressure (ICP) caused by bacterial invasion and the host response to infection. Antibiotic therapy is a sine qua non, and adjunct dexamethasone decreases mortality. The ICP increase may have a rapid course and death due to herniation is most often seen within the first week. Evidence regarding treatment of increased ICP in ABM is limited; this review summarises observational studies which point towards reduced mortality by applying a structured approach towards normalization of ICP in ABM.
AB - Acute bacterial meningitis (ABM) is associated with increased intracranial pressure (ICP) caused by bacterial invasion and the host response to infection. Antibiotic therapy is a sine qua non, and adjunct dexamethasone decreases mortality. The ICP increase may have a rapid course and death due to herniation is most often seen within the first week. Evidence regarding treatment of increased ICP in ABM is limited; this review summarises observational studies which point towards reduced mortality by applying a structured approach towards normalization of ICP in ABM.
KW - Anti-Bacterial Agents/therapeutic use
KW - Humans
KW - Intracranial Hypertension/drug therapy
KW - Intracranial Pressure
KW - Meningitis, Bacterial/drug therapy
M3 - Review
C2 - 38105735
SN - 0041-5782
VL - 185
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
IS - 51
M1 - V06230363
ER -