Fluorouracil induces myocardial ischemia with increases of plasma brain natriuretic peptide and lactic acid but without dysfunction of left ventricle

Søren Astrup Jensen; Philip Hasbak; Jann Mortensen; Jens Benn Sørensen

doi:10.1200/JCO.2009.27.3953

Fluorouracil induces myocardial ischemia with increases of plasma brain natriuretic peptide and lactic acid but without dysfunction of left ventricle

Søren Astrup Jensen, Philip Hasbak, Jann Mortensen, Jens Benn Sørensen

Department of Clinical Physiology, Nuclear Medicine & PET

82 Citations (Scopus)

Abstract

Fluorouracil (FU) is a cornerstone of colorectal cancer treatment; however, it has clinical and subclinical influence on the heart. This study aimed to clarify the pathophysiology, risk factors, and long-term effects of FU cardiotoxicity.

Original language	English
Journal	Journal of Clinical Oncology
Volume	28
Issue number	36
Pages (from-to)	5280-6
Number of pages	7
ISSN	0732-183X
DOIs	https://doi.org/10.1200/JCO.2009.27.3953
Publication status	Published - 20 Dec 2010

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Fluorouracil induces myocardial ischemia with increases of plasma brain natriuretic peptide and lactic acid but without dysfunction of left ventricle. / Jensen, Søren Astrup; Hasbak, Philip ; Mortensen, Jann et al.
In: Journal of Clinical Oncology, Vol. 28, No. 36, 20.12.2010, p. 5280-6.

Research output: Contribution to journal › Journal article › Research › peer-review

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Fluorouracil induces myocardial ischemia with increases of plasma brain natriuretic peptide and lactic acid but without dysfunction of left ventricle

Abstract

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