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Fish Oil Supplementation in Pregnancy and Neurodevelopment in Childhood-A Randomized Clinical Trial

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@article{c3be042247a146c3ae07e38de1bec86b,
title = "Fish Oil Supplementation in Pregnancy and Neurodevelopment in Childhood-A Randomized Clinical Trial",
abstract = "A double-blind randomized controlled trial of n-3 long-chain polyunsaturated fatty acid (n-3 LCPUFA) supplementation or matching placebo during third trimester of pregnancy was conducted within the COPSAC2010 mother-child cohort consisting of 736 women and their children. The objective was to determine if maternal n-3 LCPUFA pregnancy supplementation affects offspring neurodevelopment until 6 years. Neurodevelopment was evaluated in 654 children assessing age of motor milestone achievement, language development, cognitive development, general neurodevelopment, and emotional and behavioral problems. Maternal n-3 LCPUFA supplementation during pregnancy improved early language development and reduced the impact of emotional and behavioral problems. The n-3 LCPUFA supplementation was in boys associated with the earlier achievement of gross motor milestones, improved cognitive development, and a reduced impact of emotional and behavioral problems.",
author = "Laerke Sass and El{\'i}n Bjarnad{\'o}ttir and Jakob Stokholm and Bo Chawes and Vinding, {Rebecca K} and Mora-Jensen, {Anna-Rosa C} and Jonathan Thorsen and Sarah Noergaard and Ebdrup, {Bj{\o}rn H} and Jepsen, {Jens R M} and Birgitte Fagerlund and Klaus B{\o}nnelykke and Lotte Lauritzen and Hans Bisgaard",
note = "Publisher Copyright: {\textcopyright} 2021 Society for Research in Child Development Copyright: Copyright 2021 Elsevier B.V., All rights reserved.",
year = "2021",
month = jul,
doi = "10.1111/cdev.13541",
language = "English",
volume = "92",
pages = "1624--1635",
journal = "Child Development",
issn = "0009-3920",
publisher = "Wiley-Blackwell Publishing, Inc",
number = "4",

}

RIS

TY - JOUR

T1 - Fish Oil Supplementation in Pregnancy and Neurodevelopment in Childhood-A Randomized Clinical Trial

AU - Sass, Laerke

AU - Bjarnadóttir, Elín

AU - Stokholm, Jakob

AU - Chawes, Bo

AU - Vinding, Rebecca K

AU - Mora-Jensen, Anna-Rosa C

AU - Thorsen, Jonathan

AU - Noergaard, Sarah

AU - Ebdrup, Bjørn H

AU - Jepsen, Jens R M

AU - Fagerlund, Birgitte

AU - Bønnelykke, Klaus

AU - Lauritzen, Lotte

AU - Bisgaard, Hans

N1 - Publisher Copyright: © 2021 Society for Research in Child Development Copyright: Copyright 2021 Elsevier B.V., All rights reserved.

PY - 2021/7

Y1 - 2021/7

N2 - A double-blind randomized controlled trial of n-3 long-chain polyunsaturated fatty acid (n-3 LCPUFA) supplementation or matching placebo during third trimester of pregnancy was conducted within the COPSAC2010 mother-child cohort consisting of 736 women and their children. The objective was to determine if maternal n-3 LCPUFA pregnancy supplementation affects offspring neurodevelopment until 6 years. Neurodevelopment was evaluated in 654 children assessing age of motor milestone achievement, language development, cognitive development, general neurodevelopment, and emotional and behavioral problems. Maternal n-3 LCPUFA supplementation during pregnancy improved early language development and reduced the impact of emotional and behavioral problems. The n-3 LCPUFA supplementation was in boys associated with the earlier achievement of gross motor milestones, improved cognitive development, and a reduced impact of emotional and behavioral problems.

AB - A double-blind randomized controlled trial of n-3 long-chain polyunsaturated fatty acid (n-3 LCPUFA) supplementation or matching placebo during third trimester of pregnancy was conducted within the COPSAC2010 mother-child cohort consisting of 736 women and their children. The objective was to determine if maternal n-3 LCPUFA pregnancy supplementation affects offspring neurodevelopment until 6 years. Neurodevelopment was evaluated in 654 children assessing age of motor milestone achievement, language development, cognitive development, general neurodevelopment, and emotional and behavioral problems. Maternal n-3 LCPUFA supplementation during pregnancy improved early language development and reduced the impact of emotional and behavioral problems. The n-3 LCPUFA supplementation was in boys associated with the earlier achievement of gross motor milestones, improved cognitive development, and a reduced impact of emotional and behavioral problems.

UR - http://www.scopus.com/inward/record.url?scp=85100003510&partnerID=8YFLogxK

U2 - 10.1111/cdev.13541

DO - 10.1111/cdev.13541

M3 - Journal article

C2 - 33506965

VL - 92

SP - 1624

EP - 1635

JO - Child Development

JF - Child Development

SN - 0009-3920

IS - 4

ER -

ID: 62084296